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Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry

BACKGROUND: Data concerning the comparison between transcatheter aortic valve implantation and surgical aortic valve replacement in a real-world setting are scarce and in Central and Eastern Europe no such data exist. In this study, we aimed at analyzing retrospectively the characteristics and outco...

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Autores principales: Wilczek, Krzysztof, Hawranek, Michal, Wojakowski, Wojciech, Chodór, Piotr, Zembala, Michal, Buszman, Pawel, Bochenek, Andrzej, Deja, Marek, Dyrbus, Maciej, Ciesla, Daniel, Kalarus, Zbigniew, Gasior, Mariusz, Zembala, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish Society of Cardiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366412/
https://www.ncbi.nlm.nih.gov/pubmed/35346903
http://dx.doi.org/10.5152/AnatolJCardiol.2021.83009
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author Wilczek, Krzysztof
Hawranek, Michal
Wojakowski, Wojciech
Chodór, Piotr
Zembala, Michal
Buszman, Pawel
Bochenek, Andrzej
Deja, Marek
Dyrbus, Maciej
Ciesla, Daniel
Kalarus, Zbigniew
Gasior, Mariusz
Zembala, Marian
author_facet Wilczek, Krzysztof
Hawranek, Michal
Wojakowski, Wojciech
Chodór, Piotr
Zembala, Michal
Buszman, Pawel
Bochenek, Andrzej
Deja, Marek
Dyrbus, Maciej
Ciesla, Daniel
Kalarus, Zbigniew
Gasior, Mariusz
Zembala, Marian
author_sort Wilczek, Krzysztof
collection PubMed
description BACKGROUND: Data concerning the comparison between transcatheter aortic valve implantation and surgical aortic valve replacement in a real-world setting are scarce and in Central and Eastern Europe no such data exist. In this study, we aimed at analyzing retrospectively the characteristics and outcome of patients with aortic stenosis treated either with surgical aortic valve replacement or transcatheter aortic valve implantation between 2006 and 2016 in the Silesian Province, Poland in a representative real-world cohort. METHODS: In the Silesian Cardiovascular Database we retrospectively identified 5186 patients who received either transcatheter aortic valve implantation or surgical aortic valve replacement in 1 of 3 tertiary cardiovascular centers. Baseline characteristics, including relevant clinical history, and outcomes were compared before and after propensity-score matching of both groups, with 348 pairs of patients constituting the propensity-matched study cohort. The primary end-point was 24-month all-cause mortality. RESULTS: Preoperative characteristics of propensity-matched groups were similar. There was no difference between transcatheter aortic valve implantation and surgical aortic valve replacement groups with respect to the death rate at 2 years (19.9% vs. 15.6%; P = .479). In the transcatheter aortic valve implantation group, cardiac resynchronization therapy devices were more frequently implanted after the procedure (3.7% vs. 0.0, P < .001). The groups had similar rates of myocardial infarction, stroke, and re-hospitalization. Hospital stay in the matched groups was shorter after transcatheter aortic valve implantation: 14.1 versus 15.7 days (P < .001). CONCLUSIONS: At 24 months, transcatheter aortic valve implantation patients had similar outcomes as surgical aortic valve replacement except for a higher rate of cardiac resynchronization therapy device implantation and shorter hospital stay.
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spelling pubmed-93664122022-08-18 Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry Wilczek, Krzysztof Hawranek, Michal Wojakowski, Wojciech Chodór, Piotr Zembala, Michal Buszman, Pawel Bochenek, Andrzej Deja, Marek Dyrbus, Maciej Ciesla, Daniel Kalarus, Zbigniew Gasior, Mariusz Zembala, Marian Anatol J Cardiol Original Investigation BACKGROUND: Data concerning the comparison between transcatheter aortic valve implantation and surgical aortic valve replacement in a real-world setting are scarce and in Central and Eastern Europe no such data exist. In this study, we aimed at analyzing retrospectively the characteristics and outcome of patients with aortic stenosis treated either with surgical aortic valve replacement or transcatheter aortic valve implantation between 2006 and 2016 in the Silesian Province, Poland in a representative real-world cohort. METHODS: In the Silesian Cardiovascular Database we retrospectively identified 5186 patients who received either transcatheter aortic valve implantation or surgical aortic valve replacement in 1 of 3 tertiary cardiovascular centers. Baseline characteristics, including relevant clinical history, and outcomes were compared before and after propensity-score matching of both groups, with 348 pairs of patients constituting the propensity-matched study cohort. The primary end-point was 24-month all-cause mortality. RESULTS: Preoperative characteristics of propensity-matched groups were similar. There was no difference between transcatheter aortic valve implantation and surgical aortic valve replacement groups with respect to the death rate at 2 years (19.9% vs. 15.6%; P = .479). In the transcatheter aortic valve implantation group, cardiac resynchronization therapy devices were more frequently implanted after the procedure (3.7% vs. 0.0, P < .001). The groups had similar rates of myocardial infarction, stroke, and re-hospitalization. Hospital stay in the matched groups was shorter after transcatheter aortic valve implantation: 14.1 versus 15.7 days (P < .001). CONCLUSIONS: At 24 months, transcatheter aortic valve implantation patients had similar outcomes as surgical aortic valve replacement except for a higher rate of cardiac resynchronization therapy device implantation and shorter hospital stay. Turkish Society of Cardiology 2022-03-01 /pmc/articles/PMC9366412/ /pubmed/35346903 http://dx.doi.org/10.5152/AnatolJCardiol.2021.83009 Text en © Copyright 2022 authors https://creativecommons.org/licenses/by-nc/4.0/ Content of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Original Investigation
Wilczek, Krzysztof
Hawranek, Michal
Wojakowski, Wojciech
Chodór, Piotr
Zembala, Michal
Buszman, Pawel
Bochenek, Andrzej
Deja, Marek
Dyrbus, Maciej
Ciesla, Daniel
Kalarus, Zbigniew
Gasior, Mariusz
Zembala, Marian
Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry
title Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry
title_full Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry
title_fullStr Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry
title_full_unstemmed Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry
title_short Transcatheter Versus Surgical Valve Replacement: A 24-months Propensity-matched Analysis of the SILCARD Registry
title_sort transcatheter versus surgical valve replacement: a 24-months propensity-matched analysis of the silcard registry
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366412/
https://www.ncbi.nlm.nih.gov/pubmed/35346903
http://dx.doi.org/10.5152/AnatolJCardiol.2021.83009
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