Current therapy option for necrotizing enterocolitis: Practicalities and challenge

Necrotizing enterocolitis (NEC) is one of the most prevalent neonatal gastrointestinal disorders. Despite ongoing breakthroughs in its treatment and prevention, the incidence and mortality associated with NEC remain high. New therapeutic approaches, such as breast milk composition administration, st...

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Autores principales: Wu, Huihuan, Guo, Kehang, Zhuo, Zewei, Zeng, Ruijie, Luo, Yujun, Yang, Qi, Li, Jingwei, Jiang, Rui, Huang, Zena, Sha, Weihong, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366471/
https://www.ncbi.nlm.nih.gov/pubmed/35967586
http://dx.doi.org/10.3389/fped.2022.954735
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author Wu, Huihuan
Guo, Kehang
Zhuo, Zewei
Zeng, Ruijie
Luo, Yujun
Yang, Qi
Li, Jingwei
Jiang, Rui
Huang, Zena
Sha, Weihong
Chen, Hao
author_facet Wu, Huihuan
Guo, Kehang
Zhuo, Zewei
Zeng, Ruijie
Luo, Yujun
Yang, Qi
Li, Jingwei
Jiang, Rui
Huang, Zena
Sha, Weihong
Chen, Hao
author_sort Wu, Huihuan
collection PubMed
description Necrotizing enterocolitis (NEC) is one of the most prevalent neonatal gastrointestinal disorders. Despite ongoing breakthroughs in its treatment and prevention, the incidence and mortality associated with NEC remain high. New therapeutic approaches, such as breast milk composition administration, stem cell therapy, immunotherapy, and fecal microbiota transplantation (FMT) have recently evolved the prevention and the treatment of NEC. This study investigated the most recent advances in NEC therapeutic approaches and discussed their applicability to bring new insight to NEC treatment.
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spelling pubmed-93664712022-08-12 Current therapy option for necrotizing enterocolitis: Practicalities and challenge Wu, Huihuan Guo, Kehang Zhuo, Zewei Zeng, Ruijie Luo, Yujun Yang, Qi Li, Jingwei Jiang, Rui Huang, Zena Sha, Weihong Chen, Hao Front Pediatr Pediatrics Necrotizing enterocolitis (NEC) is one of the most prevalent neonatal gastrointestinal disorders. Despite ongoing breakthroughs in its treatment and prevention, the incidence and mortality associated with NEC remain high. New therapeutic approaches, such as breast milk composition administration, stem cell therapy, immunotherapy, and fecal microbiota transplantation (FMT) have recently evolved the prevention and the treatment of NEC. This study investigated the most recent advances in NEC therapeutic approaches and discussed their applicability to bring new insight to NEC treatment. Frontiers Media S.A. 2022-07-28 /pmc/articles/PMC9366471/ /pubmed/35967586 http://dx.doi.org/10.3389/fped.2022.954735 Text en Copyright © 2022 Wu, Guo, Zhuo, Zeng, Luo, Yang, Li, Jiang, Huang, Sha and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Wu, Huihuan
Guo, Kehang
Zhuo, Zewei
Zeng, Ruijie
Luo, Yujun
Yang, Qi
Li, Jingwei
Jiang, Rui
Huang, Zena
Sha, Weihong
Chen, Hao
Current therapy option for necrotizing enterocolitis: Practicalities and challenge
title Current therapy option for necrotizing enterocolitis: Practicalities and challenge
title_full Current therapy option for necrotizing enterocolitis: Practicalities and challenge
title_fullStr Current therapy option for necrotizing enterocolitis: Practicalities and challenge
title_full_unstemmed Current therapy option for necrotizing enterocolitis: Practicalities and challenge
title_short Current therapy option for necrotizing enterocolitis: Practicalities and challenge
title_sort current therapy option for necrotizing enterocolitis: practicalities and challenge
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366471/
https://www.ncbi.nlm.nih.gov/pubmed/35967586
http://dx.doi.org/10.3389/fped.2022.954735
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