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Early results of bare metal extension stent for thoracoabdominal aortic dissection

OBJECTIVES: Debakey type I and IIIb aortic dissections are complicated by extension along the full length of the aorta. Over the long term, the thoracoabdominal aorta in these patients often continues to degenerate, requiring endovascular or open repair. The purpose of this investigation is to deter...

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Autores principales: Vargo, Patrick R., Tarola, Christopher L., Durbak, Emily, Doh, Chang Yoon, Caputo, Francis J., Smolock, Christopher J., Roselli, Eric E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366534/
https://www.ncbi.nlm.nih.gov/pubmed/35967241
http://dx.doi.org/10.1016/j.xjtc.2022.04.011
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author Vargo, Patrick R.
Tarola, Christopher L.
Durbak, Emily
Doh, Chang Yoon
Caputo, Francis J.
Smolock, Christopher J.
Roselli, Eric E.
author_facet Vargo, Patrick R.
Tarola, Christopher L.
Durbak, Emily
Doh, Chang Yoon
Caputo, Francis J.
Smolock, Christopher J.
Roselli, Eric E.
author_sort Vargo, Patrick R.
collection PubMed
description OBJECTIVES: Debakey type I and IIIb aortic dissections are complicated by extension along the full length of the aorta. Over the long term, the thoracoabdominal aorta in these patients often continues to degenerate, requiring endovascular or open repair. The purpose of this investigation is to determine the early clinical outcome on aortic remodeling using a composite thoracic stent graft and thoracoabdominal bare metal extension stenting strategy. METHODS: From April 2019 to April 2021, 73 patients with Debakey I/IIIb aortic dissection underwent endovascular stent graft repair of the descending thoracic aorta and repair of the thoracoabdominal aorta using bare metal extension stenting. Preoperative and follow-up surveillance computed tomography imaging scans were analyzed. RESULTS: Fifty-three (73%) patients had a Debakey I aortic dissection, and 50 (69%) patients underwent surgery during the chronic (time to surgery >30 days) dissection phase. Mortality at 30 days was 4% (3 hyperacute patients). Stroke occurred in 3 (4%), paraparesis in 2 (2.7%), and acute renal failure requiring dialysis occurred in 2 (2.7%) patients. On postoperative and follow-up computed tomography, there was a significant increase in false lumen thrombosis (P < .001). This coincided with a significant increase in true lumen fraction suggestive of positive aortic remodeling (P < .001) at the time of latest follow-up. CONCLUSIONS: Altering the course of aortic remodeling, with placement of a dissection stent in the thoracoabdominal aorta simultaneous with descending thoracic aortic repair may promote true lumen re-expansion and false lumen thrombosis during acute and chronic dissection phases.
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spelling pubmed-93665342022-08-12 Early results of bare metal extension stent for thoracoabdominal aortic dissection Vargo, Patrick R. Tarola, Christopher L. Durbak, Emily Doh, Chang Yoon Caputo, Francis J. Smolock, Christopher J. Roselli, Eric E. JTCVS Tech Adult: Aorta OBJECTIVES: Debakey type I and IIIb aortic dissections are complicated by extension along the full length of the aorta. Over the long term, the thoracoabdominal aorta in these patients often continues to degenerate, requiring endovascular or open repair. The purpose of this investigation is to determine the early clinical outcome on aortic remodeling using a composite thoracic stent graft and thoracoabdominal bare metal extension stenting strategy. METHODS: From April 2019 to April 2021, 73 patients with Debakey I/IIIb aortic dissection underwent endovascular stent graft repair of the descending thoracic aorta and repair of the thoracoabdominal aorta using bare metal extension stenting. Preoperative and follow-up surveillance computed tomography imaging scans were analyzed. RESULTS: Fifty-three (73%) patients had a Debakey I aortic dissection, and 50 (69%) patients underwent surgery during the chronic (time to surgery >30 days) dissection phase. Mortality at 30 days was 4% (3 hyperacute patients). Stroke occurred in 3 (4%), paraparesis in 2 (2.7%), and acute renal failure requiring dialysis occurred in 2 (2.7%) patients. On postoperative and follow-up computed tomography, there was a significant increase in false lumen thrombosis (P < .001). This coincided with a significant increase in true lumen fraction suggestive of positive aortic remodeling (P < .001) at the time of latest follow-up. CONCLUSIONS: Altering the course of aortic remodeling, with placement of a dissection stent in the thoracoabdominal aorta simultaneous with descending thoracic aortic repair may promote true lumen re-expansion and false lumen thrombosis during acute and chronic dissection phases. Elsevier 2022-04-20 /pmc/articles/PMC9366534/ /pubmed/35967241 http://dx.doi.org/10.1016/j.xjtc.2022.04.011 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Adult: Aorta
Vargo, Patrick R.
Tarola, Christopher L.
Durbak, Emily
Doh, Chang Yoon
Caputo, Francis J.
Smolock, Christopher J.
Roselli, Eric E.
Early results of bare metal extension stent for thoracoabdominal aortic dissection
title Early results of bare metal extension stent for thoracoabdominal aortic dissection
title_full Early results of bare metal extension stent for thoracoabdominal aortic dissection
title_fullStr Early results of bare metal extension stent for thoracoabdominal aortic dissection
title_full_unstemmed Early results of bare metal extension stent for thoracoabdominal aortic dissection
title_short Early results of bare metal extension stent for thoracoabdominal aortic dissection
title_sort early results of bare metal extension stent for thoracoabdominal aortic dissection
topic Adult: Aorta
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366534/
https://www.ncbi.nlm.nih.gov/pubmed/35967241
http://dx.doi.org/10.1016/j.xjtc.2022.04.011
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