Cargando…

A contemporary understanding of iron metabolism in active premenopausal females

Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and contribute to variations in iron parameters throughout...

Descripción completa

Detalles Bibliográficos
Autores principales: Badenhorst, Claire E., Forsyth, Adrienne K., Govus, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366739/
https://www.ncbi.nlm.nih.gov/pubmed/35966107
http://dx.doi.org/10.3389/fspor.2022.903937
_version_ 1784765633493204992
author Badenhorst, Claire E.
Forsyth, Adrienne K.
Govus, Andrew D.
author_facet Badenhorst, Claire E.
Forsyth, Adrienne K.
Govus, Andrew D.
author_sort Badenhorst, Claire E.
collection PubMed
description Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and contribute to variations in iron parameters throughout the menstrual cycle. Despite the high prevalence of iron deficiency in premenopausal females, scant research has investigated female-specific causes and treatments for iron deficiency. In this review, we provide a comprehensive discussion of factors that influence iron status in active premenopausal females, with a focus on the menstrual cycle. We also outline several practical guidelines for monitoring, diagnosing, and treating iron deficiency in premenopausal females. Finally, we highlight several areas for further research to enhance the understanding of iron metabolism in this at-risk population.
format Online
Article
Text
id pubmed-9366739
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-93667392022-08-12 A contemporary understanding of iron metabolism in active premenopausal females Badenhorst, Claire E. Forsyth, Adrienne K. Govus, Andrew D. Front Sports Act Living Sports and Active Living Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and contribute to variations in iron parameters throughout the menstrual cycle. Despite the high prevalence of iron deficiency in premenopausal females, scant research has investigated female-specific causes and treatments for iron deficiency. In this review, we provide a comprehensive discussion of factors that influence iron status in active premenopausal females, with a focus on the menstrual cycle. We also outline several practical guidelines for monitoring, diagnosing, and treating iron deficiency in premenopausal females. Finally, we highlight several areas for further research to enhance the understanding of iron metabolism in this at-risk population. Frontiers Media S.A. 2022-07-28 /pmc/articles/PMC9366739/ /pubmed/35966107 http://dx.doi.org/10.3389/fspor.2022.903937 Text en Copyright © 2022 Badenhorst, Forsyth and Govus. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Sports and Active Living
Badenhorst, Claire E.
Forsyth, Adrienne K.
Govus, Andrew D.
A contemporary understanding of iron metabolism in active premenopausal females
title A contemporary understanding of iron metabolism in active premenopausal females
title_full A contemporary understanding of iron metabolism in active premenopausal females
title_fullStr A contemporary understanding of iron metabolism in active premenopausal females
title_full_unstemmed A contemporary understanding of iron metabolism in active premenopausal females
title_short A contemporary understanding of iron metabolism in active premenopausal females
title_sort contemporary understanding of iron metabolism in active premenopausal females
topic Sports and Active Living
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366739/
https://www.ncbi.nlm.nih.gov/pubmed/35966107
http://dx.doi.org/10.3389/fspor.2022.903937
work_keys_str_mv AT badenhorstclairee acontemporaryunderstandingofironmetabolisminactivepremenopausalfemales
AT forsythadriennek acontemporaryunderstandingofironmetabolisminactivepremenopausalfemales
AT govusandrewd acontemporaryunderstandingofironmetabolisminactivepremenopausalfemales
AT badenhorstclairee contemporaryunderstandingofironmetabolisminactivepremenopausalfemales
AT forsythadriennek contemporaryunderstandingofironmetabolisminactivepremenopausalfemales
AT govusandrewd contemporaryunderstandingofironmetabolisminactivepremenopausalfemales