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Incorporation of Indoylated Phenylalanine Yields a Sub-Micromolar Selective Melanocortin-4 Receptor Antagonist Tetrapeptide

[Image: see text] The melanocortin family is involved in many physiological functions, including pigmentation, steroidogenesis, and appetite. The centrally expressed melanocortin-3 and melanocortin-4 receptors (MC3R and MC4R) possess overlapping but distinct roles in energy homeostasis. Herein, the...

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Detalles Bibliográficos
Autores principales:	Ericson, Mark D., Larson, Courtney M., Freeman, Katie T., Nicke, Lennart, Geyer, Armin, Haskell-Luevano, Carrie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366794/ https://www.ncbi.nlm.nih.gov/pubmed/35967074 http://dx.doi.org/10.1021/acsomega.2c03307

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