Condensation properties of stress granules and processing bodies are compromised in myotonic dystrophy type 1

RNA regulation in mammalian cells requires complex physical compartmentalisation, using structures thought to be formed by liquid-liquid phase separation. Disruption of these structures is implicated in numerous degenerative diseases. Myotonic dystrophy type 1 (DM1) is a multi-systemic trinucleotide...

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Detalles Bibliográficos
Autores principales: Gulyurtlu, Selma, Magon, Monika S., Guest, Patrick, Papavasiliou, Panagiotis P., Morrison, Kim D., Prescott, Alan R., Sleeman, Judith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366894/
https://www.ncbi.nlm.nih.gov/pubmed/35642886
http://dx.doi.org/10.1242/dmm.049294

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