Cargando…

FGF22 deletion causes hidden hearing loss by affecting the function of inner hair cell ribbon synapses

Ribbon synapses are important structures in transmitting auditory signals from the inner hair cells (IHCs) to their corresponding spiral ganglion neurons (SGNs). Over the last few decades, deafness has been primarily attributed to the deterioration of cochlear hair cells rather than ribbon synapses....

Descripción completa

Detalles Bibliográficos
Autores principales:	Hou, Shule, Zhang, Jifang, Wu, Yan, Junmin, Chen, Yuyu, Huang, He, Baihui, Yang, Yan, Hong, Yuren, Chen, Jiarui, Yang, Jun, Li, Shuna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366910/ https://www.ncbi.nlm.nih.gov/pubmed/35966010 http://dx.doi.org/10.3389/fnmol.2022.922665

Ejemplares similares

Hidden hearing loss is associated with loss of ribbon synapses of cochlea inner hair cells
por: Song, Feng, et al.
Publicado: (2021)

Striatin Is Required for Hearing and Affects Inner Hair Cells and Ribbon Synapses
por: Nadar-Ponniah, Prathamesh T., et al.
Publicado: (2020)

Protection of Cochlear Ribbon Synapses and Prevention of Hidden Hearing Loss
por: Wei, Mei, et al.
Publicado: (2020)

Relating structure and function of inner hair cell ribbon synapses
por: Wichmann, C., et al.
Publicado: (2015)

Excess extracellular K(+) causes inner hair cell ribbon synapse degeneration
por: Zhao, Hong-Bo, et al.
Publicado: (2021)

FGF22 promotes generation of ribbon synapses through downregulating MEF2D
por: Li, Shuna, et al.
Publicado: (2020)

Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses
por: Karagulyan, Nare, et al.
Publicado: (2023)

N-Methyl-D-Aspartate Receptors Involvement in the Gentamicin-Induced Hearing Loss and Pathological Changes of Ribbon Synapse in the Mouse Cochlear Inner Hair Cells
por: Hong, Juan, et al.
Publicado: (2018)

Disruption of Otoferlin Alters the Mode of Exocytosis at the Mouse Inner Hair Cell Ribbon Synapse
por: Takago, Hideki, et al.
Publicado: (2019)

Structure and Function of the Hair Cell Ribbon Synapse
por: Nouvian, R., et al.
Publicado: (2006)

Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release
por: Chen, Junmin, et al.
Publicado: (2022)

Modeling inner hair cell ribbon synapses: response heterogeneity and efficiency of sound encoding in an idealized biophysical model
por: Gabrielaitis, Mantas, et al.
Publicado: (2013)

Functional subgroups of cochlear inner hair cell ribbon synapses differently modulate their EPSC properties in response to stimulation
por: Niwa, Mamiko, et al.
Publicado: (2021)

Role of intracellular calcium stores in hair-cell ribbon synapse
por: Castellano-Muñoz, Manuel, et al.
Publicado: (2014)

Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse Reformation
por: Lu, Xiaoling, et al.
Publicado: (2016)

Postsynaptic Recordings at Afferent Dendrites Contacting Cochlear Inner Hair Cells: Monitoring Multivesicular Release at a Ribbon Synapse
por: Grant, Lisa, et al.
Publicado: (2011)

Distinct Expression Patterns of Apoptosis and Autophagy-Associated Proteins and Genes during Postnatal Development of Spiral Ganglion Neurons in Rat
por: Hou, Shule, et al.
Publicado: (2020)

Coding Deficits in Noise-Induced Hidden Hearing Loss May Stem from Incomplete Repair of Ribbon Synapses in the Cochlea
por: Shi, Lijuan, et al.
Publicado: (2016)

Functional maturation of the exocytotic machinery at gerbil hair cell ribbon synapses
por: Johnson, Stuart L, et al.
Publicado: (2009)

In Vivo Ribbon Mobility and Turnover of Ribeye at Zebrafish Hair Cell Synapses
por: Graydon, Cole W., et al.
Publicado: (2017)

Functional and developmental changes in the inner hair cell ribbon synapses caused by Myosin VI knockout and deafness-inducing point mutation
por: Yin, Ning, et al.
Publicado: (2023)

Pseudo-Temporal Analysis of Single-Cell RNA Sequencing Reveals Trans-Differentiation Potential of Greater Epithelial Ridge Cells Into Hair Cells During Postnatal Development of Cochlea in Rats
por: Chen, Jianyong, et al.
Publicado: (2022)

Ribbon Synapses and Hearing Impairment in Mice After in utero Sevoflurane Exposure
por: Yuan, Xia, et al.
Publicado: (2020)

Multiple Sevoflurane Exposures During the Neonatal Period Cause Hearing Impairment and Loss of Hair Cell Ribbon Synapses in Adult Mice
por: Li, Yufeng, et al.
Publicado: (2022)

The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse
por: Becker, Lars, et al.
Publicado: (2018)

Brevican “nets” voltage-gated calcium channels at the hair cell ribbon synapse
por: Coate, Thomas M., et al.
Publicado: (2018)

Cnr2 Is Important for Ribbon Synapse Maturation and Function in Hair Cells and Photoreceptors
por: Colón-Cruz, Luis, et al.
Publicado: (2021)

Dietary intake of deuterium oxide decreases cochlear metabolism and oxidative stress levels in a mouse model of age-related hearing loss
por: Hou, Shule, et al.
Publicado: (2022)

Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses
por: Johnson, Stuart L., et al.
Publicado: (2013)

Pathological mechanisms of connexin26-related hearing loss: Potassium recycling, ATP-calcium signaling, or energy supply?
por: Chen, Penghui, et al.
Publicado: (2022)

The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
por: Calvet, Charlotte, et al.
Publicado: (2022)

Ribbon Synapses and Retinal Disease: Review
por: Frederick, Courtney E., et al.
Publicado: (2023)

Treatment with Piribedil and Memantine Reduces Noise-Induced Loss of Inner Hair Cell Synaptic Ribbons
por: Altschuler, Richard A., et al.
Publicado: (2016)

Long-term treatment with salicylate enables NMDA receptors and impairs AMPA receptors in C57BL/6J mice inner hair cell ribbon synapse
por: Cui, Wanming, et al.
Publicado: (2019)

SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves
por: Zu, Mian, et al.
Publicado: (2021)

Nanomachinery Organizing Release at Neuronal and Ribbon Synapses
por: Chakrabarti, Rituparna, et al.
Publicado: (2019)

Hearing Protection Outcomes of Analog Electrode Arrays Coated with Different Drug-Eluting Polymer Films Implanted into Guinea Pig Cochleae
por: Huang, Yuyu, et al.
Publicado: (2021)

Failure Of Hearing Acquisition in Mice With Reduced Expression of Connexin 26 Correlates With the Abnormal Phasing of Apoptosis Relative to Autophagy and Defective ATP-Dependent Ca(2+) Signaling in Kölliker’s Organ
por: Sun, Lianhua, et al.
Publicado: (2022)

MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea
por: Ikäheimo, Kuu, et al.
Publicado: (2021)

Elementary properties of Ca(2+) channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses
por: Magistretti, Jacopo, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_leoao7g736b4a8ef49d5busro8