Upregulation of Netrin-1 in the hippocampus mediates the formation of visceral hypersensitivity induced by maternal separation

Early adverse life events (EALs), such as maternal separation (MS), can cause visceral hypersensitivity, which is thought to be a key pathophysiological mechanism of irritable bowel syndrome (IBS). Previous studies mainly focused on EALs-induced visceral hypersensitivity in adulthood but did not con...

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Detalles Bibliográficos
Autores principales: Wang, Junwen, Duan, Guangbing, Zhan, Tingting, Dong, Zhiyu, Zhang, Yan, Chen, Ying, Sun, Huihui, Xu, Shuchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366914/
https://www.ncbi.nlm.nih.gov/pubmed/35966013
http://dx.doi.org/10.3389/fnmol.2022.908911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366914/
https://www.ncbi.nlm.nih.gov/pubmed/35966013
http://dx.doi.org/10.3389/fnmol.2022.908911

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