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Upregulation of Netrin-1 in the hippocampus mediates the formation of visceral hypersensitivity induced by maternal separation
Early adverse life events (EALs), such as maternal separation (MS), can cause visceral hypersensitivity, which is thought to be a key pathophysiological mechanism of irritable bowel syndrome (IBS). Previous studies mainly focused on EALs-induced visceral hypersensitivity in adulthood but did not con...
Autores principales: | Wang, Junwen, Duan, Guangbing, Zhan, Tingting, Dong, Zhiyu, Zhang, Yan, Chen, Ying, Sun, Huihui, Xu, Shuchang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366914/ https://www.ncbi.nlm.nih.gov/pubmed/35966013 http://dx.doi.org/10.3389/fnmol.2022.908911 |
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