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Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3

Spinocerebellar ataxia type 3 (SCA3) is an adult-onset, progressive ataxia. SCA3 presents with ataxia before any gross neuropathology. A feature of many cerebellar ataxias is aberrant cerebellar output that contributes to motor dysfunction. We examined whether abnormal cerebellar output was present...

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Detalles Bibliográficos
Autores principales: Mayoral-Palarz, Kristin, Neves-Carvalho, Andreia, Duarte-Silva, Sara, Monteiro-Fernandes, Daniela, Maciel, Patrícia, Khodakhah, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367011/
https://www.ncbi.nlm.nih.gov/pubmed/35660856
http://dx.doi.org/10.1242/dmm.049514

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