From strain engineering to process development: monoclonal antibody production with an unnatural amino acid in Pichia pastoris

BACKGROUND: Expansion of the genetic code is a frequently employed approach for the modification of recombinant protein properties. It involves reassignment of a codon to another, e.g., unnatural, amino acid and requires the action of a pair of orthogonal tRNA and aminoacyl tRNA synthetase modified...

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Detalles Bibliográficos
Autores principales: Tir, Nora, Heistinger, Lina, Grünwald-Gruber, Clemens, Jakob, Leo A., Dickgiesser, Stephan, Rasche, Nicolas, Mattanovich, Diethard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367057/
https://www.ncbi.nlm.nih.gov/pubmed/35953849
http://dx.doi.org/10.1186/s12934-022-01882-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367057/
https://www.ncbi.nlm.nih.gov/pubmed/35953849
http://dx.doi.org/10.1186/s12934-022-01882-6

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