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Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups

BACKGROUND: Interleukin 6 (IL-6) signaling is being investigated as a therapeutic target for atherosclerotic cardiovascular disease (CVD). While changes in circulating high-sensitivity C-reactive protein (hsCRP) are used as a marker of IL-6 signaling, it is not known whether there is effect heteroge...

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Detalles Bibliográficos
Autores principales:	Georgakis, Marios K., Malik, Rainer, Richardson, Tom G., Howson, Joanna M. M., Anderson, Christopher D., Burgess, Stephen, Hovingh, G. Kees, Dichgans, Martin, Gill, Dipender
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367072/ https://www.ncbi.nlm.nih.gov/pubmed/35948913 http://dx.doi.org/10.1186/s12916-022-02446-6

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