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Nectin-4 promotes osteosarcoma progression and metastasis through activating PI3K/AKT/NF-κB signaling by down-regulation of miR-520c-3p
PURPOSE: Nectin-4 is specifically up-regulated in various tumors, exert crucial effects on tumor occurrence and development. Nevertheless, the role and molecular mechanism of Nectin-4 in osteosarcoma (OS) are rarely studied. METHODS: The expression of Nectin-4 and its relationship with clinical char...
Autores principales: | Liu, Yongheng, Li, Guanghao, Zhang, Yan, Li, Lili, Zhang, Yanting, Huang, Xiaoyu, Wei, Xianfu, Zhou, Peng, Liu, Ming, zhao, Gang, Feng, Jinyan, Wang, Guowen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367085/ https://www.ncbi.nlm.nih.gov/pubmed/35953862 http://dx.doi.org/10.1186/s12935-022-02669-w |
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