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Modular reconstruction and optimization of the trans-4-hydroxy-L-proline synthesis pathway in Escherichia coli
BACKGROUND: In recent years, there has been a growing demand for microbial production of trans-4-hydroxy-L-proline (t4Hyp), which is a value-added amino acid and has been widely used in the fields of medicine, food, and cosmetics. In this study, a multivariate modular metabolic engineering approach...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367115/ https://www.ncbi.nlm.nih.gov/pubmed/35953819 http://dx.doi.org/10.1186/s12934-022-01884-4 |