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Modular reconstruction and optimization of the trans-4-hydroxy-L-proline synthesis pathway in Escherichia coli

BACKGROUND: In recent years, there has been a growing demand for microbial production of trans-4-hydroxy-L-proline (t4Hyp), which is a value-added amino acid and has been widely used in the fields of medicine, food, and cosmetics. In this study, a multivariate modular metabolic engineering approach...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhenyu, Su, Weike, Bao, Yunyun, Huang, Qianqian, Ye, Kai, Liu, Pengfu, Chu, Xiaohe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367115/ https://www.ncbi.nlm.nih.gov/pubmed/35953819 http://dx.doi.org/10.1186/s12934-022-01884-4

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