Multifaceted roles of extracellular RNAs in different diseases

Extracellular RNAs (exRNAs) are novel circulating factors that can be used as biomarkers in various diseases. Their unique and diverse kinds, as well as their role as biomarkers, make them significant biomarkers. There has been immense work carried out since the discovery of exRNAs in circulation an...

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Autores principales: Sohail, Abdullah Muhammad, Khawar, Muhammad Babar, Afzal, Ali, Hassan, Ali, Shahzaman, Sara, Ali, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367134/
https://www.ncbi.nlm.nih.gov/pubmed/35948986
http://dx.doi.org/10.1186/s40779-022-00405-z
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author Sohail, Abdullah Muhammad
Khawar, Muhammad Babar
Afzal, Ali
Hassan, Ali
Shahzaman, Sara
Ali, Ahmed
author_facet Sohail, Abdullah Muhammad
Khawar, Muhammad Babar
Afzal, Ali
Hassan, Ali
Shahzaman, Sara
Ali, Ahmed
author_sort Sohail, Abdullah Muhammad
collection PubMed
description Extracellular RNAs (exRNAs) are novel circulating factors that can be used as biomarkers in various diseases. Their unique and diverse kinds, as well as their role as biomarkers, make them significant biomarkers. There has been immense work carried out since the discovery of exRNAs in circulation and other biological fluids to catalog and determine whether exRNAs may be utilized as indicators for health and illness. In this review, we aim to understand the current state of exRNAs in relation to various diseases and their potential as biomarkers. We will also review current issues and challenges faced in using exRNAs, with clinical and lab trials, that can be used as viable markers for different diseases.
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spelling pubmed-93671342022-08-12 Multifaceted roles of extracellular RNAs in different diseases Sohail, Abdullah Muhammad Khawar, Muhammad Babar Afzal, Ali Hassan, Ali Shahzaman, Sara Ali, Ahmed Mil Med Res Review Extracellular RNAs (exRNAs) are novel circulating factors that can be used as biomarkers in various diseases. Their unique and diverse kinds, as well as their role as biomarkers, make them significant biomarkers. There has been immense work carried out since the discovery of exRNAs in circulation and other biological fluids to catalog and determine whether exRNAs may be utilized as indicators for health and illness. In this review, we aim to understand the current state of exRNAs in relation to various diseases and their potential as biomarkers. We will also review current issues and challenges faced in using exRNAs, with clinical and lab trials, that can be used as viable markers for different diseases. BioMed Central 2022-08-11 /pmc/articles/PMC9367134/ /pubmed/35948986 http://dx.doi.org/10.1186/s40779-022-00405-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Sohail, Abdullah Muhammad
Khawar, Muhammad Babar
Afzal, Ali
Hassan, Ali
Shahzaman, Sara
Ali, Ahmed
Multifaceted roles of extracellular RNAs in different diseases
title Multifaceted roles of extracellular RNAs in different diseases
title_full Multifaceted roles of extracellular RNAs in different diseases
title_fullStr Multifaceted roles of extracellular RNAs in different diseases
title_full_unstemmed Multifaceted roles of extracellular RNAs in different diseases
title_short Multifaceted roles of extracellular RNAs in different diseases
title_sort multifaceted roles of extracellular rnas in different diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367134/
https://www.ncbi.nlm.nih.gov/pubmed/35948986
http://dx.doi.org/10.1186/s40779-022-00405-z
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