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Identification of influential probe types in epigenetic predictions of human traits: implications for microarray design
BACKGROUND: CpG methylation levels can help to explain inter-individual differences in phenotypic traits. Few studies have explored whether identifying probe subsets based on their biological and statistical properties can maximise predictions whilst minimising array content. Variance component anal...
Autores principales: | Hillary, Robert F., McCartney, Daniel L., McRae, Allan F., Campbell, Archie, Walker, Rosie M., Hayward, Caroline, Horvath, Steve, Porteous, David J., Evans, Kathryn L., Marioni, Riccardo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367152/ https://www.ncbi.nlm.nih.gov/pubmed/35948928 http://dx.doi.org/10.1186/s13148-022-01320-9 |
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