Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging

Ovarian aging is characterized by a progressive decline in ovarian function. With the increase in life expectancy worldwide, ovarian aging has gradually become a key health problem among women. Over the years, various strategies have been developed to preserve fertility in women, while there are cur...

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Autores principales: Wu, Meng, Guo, Yican, Wei, Simin, Xue, Liru, Tang, Weicheng, Chen, Dan, Xiong, Jiaqiang, Huang, Yibao, Fu, Fangfang, Wu, Chuqing, Chen, Ying, Zhou, Su, Zhang, Jinjin, Li, Yan, Wang, Wenwen, Dai, Jun, Wang, Shixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367160/
https://www.ncbi.nlm.nih.gov/pubmed/35953871
http://dx.doi.org/10.1186/s12951-022-01566-8
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author Wu, Meng
Guo, Yican
Wei, Simin
Xue, Liru
Tang, Weicheng
Chen, Dan
Xiong, Jiaqiang
Huang, Yibao
Fu, Fangfang
Wu, Chuqing
Chen, Ying
Zhou, Su
Zhang, Jinjin
Li, Yan
Wang, Wenwen
Dai, Jun
Wang, Shixuan
author_facet Wu, Meng
Guo, Yican
Wei, Simin
Xue, Liru
Tang, Weicheng
Chen, Dan
Xiong, Jiaqiang
Huang, Yibao
Fu, Fangfang
Wu, Chuqing
Chen, Ying
Zhou, Su
Zhang, Jinjin
Li, Yan
Wang, Wenwen
Dai, Jun
Wang, Shixuan
author_sort Wu, Meng
collection PubMed
description Ovarian aging is characterized by a progressive decline in ovarian function. With the increase in life expectancy worldwide, ovarian aging has gradually become a key health problem among women. Over the years, various strategies have been developed to preserve fertility in women, while there are currently no clinical treatments to delay ovarian aging. Recently, advances in biomaterials and technologies, such as three-dimensional (3D) printing and microfluidics for the encapsulation of follicles and nanoparticles as delivery systems for drugs, have shown potential to be translational strategies for ovarian aging. This review introduces the research progress on the mechanisms underlying ovarian aging, and summarizes the current state of biomaterials in the evaluation and treatment of ovarian aging, including safety, potential applications, future directions and difficulties in translation. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-93671602022-08-12 Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging Wu, Meng Guo, Yican Wei, Simin Xue, Liru Tang, Weicheng Chen, Dan Xiong, Jiaqiang Huang, Yibao Fu, Fangfang Wu, Chuqing Chen, Ying Zhou, Su Zhang, Jinjin Li, Yan Wang, Wenwen Dai, Jun Wang, Shixuan J Nanobiotechnology Review Ovarian aging is characterized by a progressive decline in ovarian function. With the increase in life expectancy worldwide, ovarian aging has gradually become a key health problem among women. Over the years, various strategies have been developed to preserve fertility in women, while there are currently no clinical treatments to delay ovarian aging. Recently, advances in biomaterials and technologies, such as three-dimensional (3D) printing and microfluidics for the encapsulation of follicles and nanoparticles as delivery systems for drugs, have shown potential to be translational strategies for ovarian aging. This review introduces the research progress on the mechanisms underlying ovarian aging, and summarizes the current state of biomaterials in the evaluation and treatment of ovarian aging, including safety, potential applications, future directions and difficulties in translation. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2022-08-11 /pmc/articles/PMC9367160/ /pubmed/35953871 http://dx.doi.org/10.1186/s12951-022-01566-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Wu, Meng
Guo, Yican
Wei, Simin
Xue, Liru
Tang, Weicheng
Chen, Dan
Xiong, Jiaqiang
Huang, Yibao
Fu, Fangfang
Wu, Chuqing
Chen, Ying
Zhou, Su
Zhang, Jinjin
Li, Yan
Wang, Wenwen
Dai, Jun
Wang, Shixuan
Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
title Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
title_full Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
title_fullStr Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
title_full_unstemmed Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
title_short Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
title_sort biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367160/
https://www.ncbi.nlm.nih.gov/pubmed/35953871
http://dx.doi.org/10.1186/s12951-022-01566-8
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