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BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas

SIMPLE SUMMARY: Uveal melanoma is a highly metastatic cancer of the eye which is notoriously resistant to therapy. Elucidating the mechanisms of metastasis in order to devise effective therapies has been a major challenge. The strongest genetic risk factor for metastasis in uveal melanoma is the mut...

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Detalles Bibliográficos
Autores principales:	Kaler, Christopher J., Dollar, James J., Cruz, Anthony M., Kuznetsoff, Jeffim N., Sanchez, Margaret I., Decatur, Christina L., Licht, Jonathan D., Smalley, Keiran S. M., Correa, Zelia M., Kurtenbach, Stefan, Harbour, J. William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367253/ https://www.ncbi.nlm.nih.gov/pubmed/35954340 http://dx.doi.org/10.3390/cancers14153678

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