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Transcriptomes of Injured Lamprey Axon Tips: Single-Cell RNA-Seq Suggests Differential Involvement of MAPK Signaling Pathways in Axon Retraction and Regeneration after Spinal Cord Injury

Axotomy in the CNS activates retrograde signals that can trigger regeneration or cell death. Whether these outcomes use different injury signals is not known. Local protein synthesis in axon tips plays an important role in axon retraction and regeneration. Microarray and RNA-seq studies on cultured...

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Detalles Bibliográficos
Autores principales: Jin, Li-Qing, Zhou, Yan, Li, Yue-Sheng, Zhang, Guixin, Hu, Jianli, Selzer, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367414/
https://www.ncbi.nlm.nih.gov/pubmed/35954164
http://dx.doi.org/10.3390/cells11152320

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