Germline Variants Associated with Nasopharyngeal Carcinoma Predisposition Identified through Whole-Exome Sequencing

SIMPLE SUMMARY: The aim of this study was to identify the germline genetic variants associated with an increased risk of developing nasopharyngeal carcinoma (NPC). DNA samples from 119 Singaporean NPC patients were sequenced, with 17 pathogenic variants in 17 genes found to be enriched in NPC patien...

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Detalles Bibliográficos
Autores principales: Lee, Ning-Yuan, Hum, Melissa, Ong, Pei-Yi, Myint, Matthew Khine, Ong, Enya H. W., Low, Kar-Perng, Li, Zheng, Goh, Boon-Cher, Tay, Joshua K., Loh, Kwok-Seng, Chua, Melvin L. K., Lee, Soo-Chin, Khor, Chiea-Chuen, Lee, Ann S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367457/
https://www.ncbi.nlm.nih.gov/pubmed/35954343
http://dx.doi.org/10.3390/cancers14153680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367457/
https://www.ncbi.nlm.nih.gov/pubmed/35954343
http://dx.doi.org/10.3390/cancers14153680

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