Cancer Associated Fibroblast (CAF) Regulation of PDAC Parenchymal (CPC) and CSC Phenotypes Is Modulated by ECM Composition

SIMPLE SUMMARY: Here, we demonstrate for the first time that ECM composition cooperates with CAFs to jointly regulate/modulate the highly dynamic interactions between the CPC and CSC cell lines and establish a continuum between tumor initiation and progression in primary PDAC tumors. Altogether, the...

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Detalles Bibliográficos
Autores principales: Cannone, Stefania, Greco, Maria Raffaella, Carvalho, Tiago M. A., Guizouarn, Helene, Soriani, Olivier, Di Molfetta, Daria, Tomasini, Richard, Zeeberg, Katrine, Reshkin, Stephan Joel, Cardone, Rosa Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367491/
https://www.ncbi.nlm.nih.gov/pubmed/35954400
http://dx.doi.org/10.3390/cancers14153737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367491/
https://www.ncbi.nlm.nih.gov/pubmed/35954400
http://dx.doi.org/10.3390/cancers14153737

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