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Integration of p16/HPV DNA Status with a 24-miRNA-Defined Molecular Phenotype Improves Clinically Relevant Stratification of Head and Neck Cancer Patients

SIMPLE SUMMARY: Human papillomavirus (HPV)-driven head and neck squamous cell carcinomas (HNSCC), regarded as a distinct clinical entity, are characterized by a considerably favourable prognosis after radio(chemo)therapy and a not yet fully understood distinct molecular pathogenesis. We aimed to dev...

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Detalles Bibliográficos
Autores principales: Hess, Julia, Unger, Kristian, Maihoefer, Cornelius, Schüttrumpf, Lars, Weber, Peter, Marschner, Sebastian, Wintergerst, Ludmila, Pflugradt, Ulrike, Baumeister, Philipp, Walch, Axel, Woischke, Christine, Kirchner, Thomas, Werner, Martin, Sörensen, Kristin, Baumann, Michael, Tinhofer, Ingeborg, Combs, Stephanie E., Debus, Jürgen, Schäfer, Henning, Krause, Mechthild, Linge, Annett, von der Grün, Jens, Stuschke, Martin, Zips, Daniel, Canis, Martin, Lauber, Kirsten, Ganswindt, Ute, Henke, Michael, Zitzelsberger, Horst, Belka, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367561/
https://www.ncbi.nlm.nih.gov/pubmed/35954409
http://dx.doi.org/10.3390/cancers14153745