Distinct immune stimulatory effects of anti-human VISTA antibodies are determined by Fc-receptor interaction

VISTA (PD-1H) is an immune regulatory molecule considered part of the next wave of immuno-oncology targets. VISTA is an immunoglobulin (Ig) superfamily cell surface molecule mainly expressed on myeloid cells, and to some extent on NK cells and T cells. In previous preclinical studies, some VISTA-tar...

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Detalles Bibliográficos
Autores principales: Mostböck, Sven, Wu, Helen Haixia, Fenn, Timothy, Riegler, Bettina, Strahlhofer, Susanne, Huang, Yining, Hansen, Gale, Kroe-Barrett, Rachel, Tirapu, Iñigo, Vogt, Anne B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367637/
https://www.ncbi.nlm.nih.gov/pubmed/35967294
http://dx.doi.org/10.3389/fimmu.2022.862757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367637/
https://www.ncbi.nlm.nih.gov/pubmed/35967294
http://dx.doi.org/10.3389/fimmu.2022.862757

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