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Differential responses to (223)Ra and Alpha-particles exposure in prostate cancer driven by mitotic catastrophe

INTRODUCTION: Radium-223 ((223)Ra) has been shown to have an overall survival benefit in metastatic castration-resistant prostate cancer (mCRPC) involving bone. Despite its increased clinical usage, relatively little is known regarding the mechanism of action of (223)Ra at the cellular level. METHOD...

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Detalles Bibliográficos
Autores principales:	Guerra Liberal, Francisco D. C., Moreira, Hugo, Redmond, Kelly M., O’Sullivan, Joe M., Alshehri, Ali H. D., Wright, Timothy C., Dunne, Victoria L., Campfield, Caoimhghin, Biggart, Sandra, McMahon, Stephen J., Prise, Kevin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367686/ https://www.ncbi.nlm.nih.gov/pubmed/35965568 http://dx.doi.org/10.3389/fonc.2022.877302

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