MALT1 regulates Th2 and Th17 differentiation via NF-κB and JNK pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis

OBJECTIVE: MALT1 regulates immunity and inflammation in multiple ways, while its role in rheumatoid arthritis (RA) is obscure. This study aimed to investigate the relationship of MALT1 with disease features, treatment outcome, as well as its effect on Th1/2/17 cell differentiation and underlying mol...

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Detalles Bibliográficos
Autores principales: Wang, Qiubo, Wang, Yapeng, Liu, Qingyang, Chu, Ying, Mi, Rui, Jiang, Fengying, Zhao, Jingjing, Hu, Kelong, Luo, Ran, Feng, Yufeng, Lee, Harrison, Zhou, Dong, Mi, Jingyi, Deng, Ruoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367691/
https://www.ncbi.nlm.nih.gov/pubmed/35967391
http://dx.doi.org/10.3389/fimmu.2022.913830

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