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BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein

Since first reported in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is rapidly acquiring mutations, particularly in the spike protein, that can modulate pathogenicity, transmission and antibody evasion leading to successive waves of COVID19 infections despite an unprecedented...

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Detalles Bibliográficos
Autores principales:	Manangeeswaran, Mohanraj, Ireland, Derek D. C., Thacker, Seth G., Lee, Ha-Na, Kelley-Baker, Logan, Lewkowicz, Aaron P., Rothlauf, Paul W., Cornejo Pontelli, Marjorie, Bloyet, Louis-Marie, Eckhaus, Michael A., Mendoza, Mirian I., Whelan, Sean, Verthelyi, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367692/ https://www.ncbi.nlm.nih.gov/pubmed/35967447 http://dx.doi.org/10.3389/fimmu.2022.919815

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