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Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes

Brain-Derived Neurotropic Factor (BDNF) is one of the essential mediating factors of exercise-induced neuroplasticity, but the underlying molecular mechanisms of exercise-induced neuroplasticity are still largely unknown. Personality dimensions differentiate individuals and depend on genes and envir...

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Autores principales: Humińska-Lisowska, Kinga, Chmielowiec, Jolanta, Chmielowiec, Krzysztof, Niewczas, Marta, Lachowicz, Milena, Cięszczyk, Paweł, Masiak, Jolanta, Strońska-Pluta, Aleksandra, Michałowska-Sawczyn, Monika, Maculewicz, Ewelina, Grzywacz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367731/
https://www.ncbi.nlm.nih.gov/pubmed/35955088
http://dx.doi.org/10.3390/ijerph19159732
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author Humińska-Lisowska, Kinga
Chmielowiec, Jolanta
Chmielowiec, Krzysztof
Niewczas, Marta
Lachowicz, Milena
Cięszczyk, Paweł
Masiak, Jolanta
Strońska-Pluta, Aleksandra
Michałowska-Sawczyn, Monika
Maculewicz, Ewelina
Grzywacz, Anna
author_facet Humińska-Lisowska, Kinga
Chmielowiec, Jolanta
Chmielowiec, Krzysztof
Niewczas, Marta
Lachowicz, Milena
Cięszczyk, Paweł
Masiak, Jolanta
Strońska-Pluta, Aleksandra
Michałowska-Sawczyn, Monika
Maculewicz, Ewelina
Grzywacz, Anna
author_sort Humińska-Lisowska, Kinga
collection PubMed
description Brain-Derived Neurotropic Factor (BDNF) is one of the essential mediating factors of exercise-induced neuroplasticity, but the underlying molecular mechanisms of exercise-induced neuroplasticity are still largely unknown. Personality dimensions differentiate individuals and depend on genes and environmental factors. The dimensions of openness to experience, emotional stability, extraversion and conscientiousness have been reported to be positively related to performance; considering agreeableness, a negative relation with sports performance was emphasized. However, not enough effort has been put into investigating the relationship between genetic polymorphisms affecting psychological abilities and competitive power sports. The aim of this study was to investigate the association of the rs6265 polymorphism of BDNF with personality dimensions in martial arts athletes. The study was conducted among martial arts athletes. The study group included 258 volunteers (martial arts athletes (n = 106) and controls (n = 152). BDNF polymorphism testing was performed using the real-time PCR method; personality dimensions were assessed using standardized NEO-FFI questionnaires. All analyses were performed using STATISTICA 13. We observed that martial arts athletes’ G/G genotypes compared to the control group G/G genotypes presented significantly higher severity of personality dimension “conscientiousness”. In comparison with the controls, the case group subjects had significantly higher scores in the dimension extraversion (M 6.89 vs. M 6.43, p = 0.0405) and conscientiousness/scale (M 7.23 vs. M 5.89, p < 0.0001). The results of 2 × 3 factorial ANOVA noticed a statistically significant effect of combined factor BDNF rs6265 genotype of martial arts/control (F(2,252) = 3.11, p = 0.0465, η(2) = 0.024). Additionally, we observed that the results of 2 × 3 factorial ANOVA showed a statistically significant influence of combined factor BDNF rs6265 of genotype martial arts/ control (F(2,252) = 6.16, p = 0.0024, η(2) = 0.047). The combination of the analysis of personality dimensions with genetics—as in the case of the polymorphism of the BDNF gene related to neuroplasticity—indicates that neurobiology cannot be ignored in educating sports champions. We already know that this is related to genetics. However, little is still known about the influence of personality traits on sports performance. We observed that martial arts athletes’ G/G genotypes, in comparison to the control group’s G/G genotypes, presented significantly higher severity of personality dimension “conscientiousness”. This is worthy of further analysis and probably longitudinal studies on a more numerous group of athletes.
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spelling pubmed-93677312022-08-12 Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes Humińska-Lisowska, Kinga Chmielowiec, Jolanta Chmielowiec, Krzysztof Niewczas, Marta Lachowicz, Milena Cięszczyk, Paweł Masiak, Jolanta Strońska-Pluta, Aleksandra Michałowska-Sawczyn, Monika Maculewicz, Ewelina Grzywacz, Anna Int J Environ Res Public Health Article Brain-Derived Neurotropic Factor (BDNF) is one of the essential mediating factors of exercise-induced neuroplasticity, but the underlying molecular mechanisms of exercise-induced neuroplasticity are still largely unknown. Personality dimensions differentiate individuals and depend on genes and environmental factors. The dimensions of openness to experience, emotional stability, extraversion and conscientiousness have been reported to be positively related to performance; considering agreeableness, a negative relation with sports performance was emphasized. However, not enough effort has been put into investigating the relationship between genetic polymorphisms affecting psychological abilities and competitive power sports. The aim of this study was to investigate the association of the rs6265 polymorphism of BDNF with personality dimensions in martial arts athletes. The study was conducted among martial arts athletes. The study group included 258 volunteers (martial arts athletes (n = 106) and controls (n = 152). BDNF polymorphism testing was performed using the real-time PCR method; personality dimensions were assessed using standardized NEO-FFI questionnaires. All analyses were performed using STATISTICA 13. We observed that martial arts athletes’ G/G genotypes compared to the control group G/G genotypes presented significantly higher severity of personality dimension “conscientiousness”. In comparison with the controls, the case group subjects had significantly higher scores in the dimension extraversion (M 6.89 vs. M 6.43, p = 0.0405) and conscientiousness/scale (M 7.23 vs. M 5.89, p < 0.0001). The results of 2 × 3 factorial ANOVA noticed a statistically significant effect of combined factor BDNF rs6265 genotype of martial arts/control (F(2,252) = 3.11, p = 0.0465, η(2) = 0.024). Additionally, we observed that the results of 2 × 3 factorial ANOVA showed a statistically significant influence of combined factor BDNF rs6265 of genotype martial arts/ control (F(2,252) = 6.16, p = 0.0024, η(2) = 0.047). The combination of the analysis of personality dimensions with genetics—as in the case of the polymorphism of the BDNF gene related to neuroplasticity—indicates that neurobiology cannot be ignored in educating sports champions. We already know that this is related to genetics. However, little is still known about the influence of personality traits on sports performance. We observed that martial arts athletes’ G/G genotypes, in comparison to the control group’s G/G genotypes, presented significantly higher severity of personality dimension “conscientiousness”. This is worthy of further analysis and probably longitudinal studies on a more numerous group of athletes. MDPI 2022-08-07 /pmc/articles/PMC9367731/ /pubmed/35955088 http://dx.doi.org/10.3390/ijerph19159732 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Humińska-Lisowska, Kinga
Chmielowiec, Jolanta
Chmielowiec, Krzysztof
Niewczas, Marta
Lachowicz, Milena
Cięszczyk, Paweł
Masiak, Jolanta
Strońska-Pluta, Aleksandra
Michałowska-Sawczyn, Monika
Maculewicz, Ewelina
Grzywacz, Anna
Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes
title Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes
title_full Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes
title_fullStr Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes
title_full_unstemmed Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes
title_short Associations of Brain-Derived Neurotropic Factor rs6265 Gene Polymorphism with Personality Dimensions among Athletes
title_sort associations of brain-derived neurotropic factor rs6265 gene polymorphism with personality dimensions among athletes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367731/
https://www.ncbi.nlm.nih.gov/pubmed/35955088
http://dx.doi.org/10.3390/ijerph19159732
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