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From IL-17 to IFN-γ in inflammatory skin disorders: Is transdifferentiation a potential treatment target?

The targeted inhibition of effector cytokines such as interleukin 17 (IL-17) in psoriasis and IL-13 in atopic dermatitis offers impressive efficacy with a favorable side effect profile. In contrast, the downregulation of interferon gamma (IFN-γ) in T helper (Th) 1-dominant skin disorders may lead to...

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Detalles Bibliográficos
Autores principales: Belpaire, Arno, van Geel, Nanja, Speeckaert, Reinhart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9367984/
https://www.ncbi.nlm.nih.gov/pubmed/35967358
http://dx.doi.org/10.3389/fimmu.2022.932265

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