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Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese

Epistasis of ERAP1 single nucleotide variations (SNVs) and HLA-B27 has been linked to ankylosing spondylitis susceptibility (AS). The current study examined how prevalent ERAP1 allelic variants (SNV haplotypes) in Taiwan affect ERAP1 functions and AS susceptibility in the presence or absence of HLA-...

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Detalles Bibliográficos
Autores principales: Wang, Chin-Man, Liu, Ming-Kun, Jan Wu, Yeong-Jian, Lin, Jing-Chi, Zheng, Jian-Wen, Wu, Jianming, Chen, Ji-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368314/
https://www.ncbi.nlm.nih.gov/pubmed/35954271
http://dx.doi.org/10.3390/cells11152427