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Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study

We aimed to identify subgroups of young children with differential risks for ADHD, and cross-validate these subgroups with an independent sample of children. All children in Study 1 (N = 120) underwent psychological assessments and were diagnosed with ADHD before age 7. Latent class analysis (LCA) c...

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Autores principales: Law, Evelyn, Sideridis, Georgios, Alkhadim, Ghadah, Snyder, Jenna, Sheridan, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368489/
https://www.ncbi.nlm.nih.gov/pubmed/35954547
http://dx.doi.org/10.3390/ijerph19159195
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author Law, Evelyn
Sideridis, Georgios
Alkhadim, Ghadah
Snyder, Jenna
Sheridan, Margaret
author_facet Law, Evelyn
Sideridis, Georgios
Alkhadim, Ghadah
Snyder, Jenna
Sheridan, Margaret
author_sort Law, Evelyn
collection PubMed
description We aimed to identify subgroups of young children with differential risks for ADHD, and cross-validate these subgroups with an independent sample of children. All children in Study 1 (N = 120) underwent psychological assessments and were diagnosed with ADHD before age 7. Latent class analysis (LCA) classified children into risk subgroups. Study 2 (N = 168) included an independent sample of children under age 7. A predictive model from Study 1 was applied to Study 2. The latent class analyses in Study 1 indicated preference of a 3-class solution (BIC = 3807.70, p < 0.001). Maternal education, income-to-needs ratio, and family history of psychopathology, defined class membership more strongly than child factors. An almost identical LCA structure from Study 1 was replicated in Study 2 (BIC = 5108.01, p < 0.001). Indices of sensitivity (0.913, 95% C.I. 0.814–0.964) and specificity (0.788, 95% C.I. 0.692–0.861) were high across studies. It is concluded that the classifications represent valid combinations of child, parent, and family characteristics that are predictive of ADHD in young children.
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spelling pubmed-93684892022-08-12 Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study Law, Evelyn Sideridis, Georgios Alkhadim, Ghadah Snyder, Jenna Sheridan, Margaret Int J Environ Res Public Health Article We aimed to identify subgroups of young children with differential risks for ADHD, and cross-validate these subgroups with an independent sample of children. All children in Study 1 (N = 120) underwent psychological assessments and were diagnosed with ADHD before age 7. Latent class analysis (LCA) classified children into risk subgroups. Study 2 (N = 168) included an independent sample of children under age 7. A predictive model from Study 1 was applied to Study 2. The latent class analyses in Study 1 indicated preference of a 3-class solution (BIC = 3807.70, p < 0.001). Maternal education, income-to-needs ratio, and family history of psychopathology, defined class membership more strongly than child factors. An almost identical LCA structure from Study 1 was replicated in Study 2 (BIC = 5108.01, p < 0.001). Indices of sensitivity (0.913, 95% C.I. 0.814–0.964) and specificity (0.788, 95% C.I. 0.692–0.861) were high across studies. It is concluded that the classifications represent valid combinations of child, parent, and family characteristics that are predictive of ADHD in young children. MDPI 2022-07-27 /pmc/articles/PMC9368489/ /pubmed/35954547 http://dx.doi.org/10.3390/ijerph19159195 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Law, Evelyn
Sideridis, Georgios
Alkhadim, Ghadah
Snyder, Jenna
Sheridan, Margaret
Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study
title Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study
title_full Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study
title_fullStr Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study
title_full_unstemmed Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study
title_short Classifying Young Children with Attention-Deficit/Hyperactivity Disorder Based on Child, Parent, and Family Characteristics: A Cross-Validation Study
title_sort classifying young children with attention-deficit/hyperactivity disorder based on child, parent, and family characteristics: a cross-validation study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368489/
https://www.ncbi.nlm.nih.gov/pubmed/35954547
http://dx.doi.org/10.3390/ijerph19159195
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