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Three Binding Conformations of BIO124 in the Pocket of the PICK1 PDZ Domain

The PDZ family has drawn attention as possible drug targets because of the domains’ wide ranges of function and highly conserved binding pockets. The PICK1 PDZ domain has been proposed as a possible drug target because the interactions between the PICK1 PDZ domain and the GluA2 subunit of the AMPA r...

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Detalles Bibliográficos
Autores principales: Stevens, Amy O., Luo, Samuel, He, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368557/
https://www.ncbi.nlm.nih.gov/pubmed/35954295
http://dx.doi.org/10.3390/cells11152451

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