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Modeling MEN1 with Patient-Origin iPSCs Reveals GLP-1R Mediated Hypersecretion of Insulin

Multiple endocrine neoplasia type 1 (MEN1) is an inherited disease caused by mutations in the MEN1 gene encoding a nuclear protein menin. Among those different endocrine tumors of MEN1, the pancreatic neuroendocrine tumors (PNETs) are life-threatening and frequently implicated. Since there are uncer...

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Detalles Bibliográficos
Autores principales:	Cheng, Ziqi, Guo, Dongsheng, Ruzi, Aynisahan, Pan, Tingcai, You, Kai, Chen, Yan, Huang, Xinping, Zhang, Jiaye, Yang, Fan, Niu, Lizhi, Xu, Kecheng, Li, Yin-Xiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368616/ https://www.ncbi.nlm.nih.gov/pubmed/35954231 http://dx.doi.org/10.3390/cells11152387

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