Cargando…

The Mechanistic Pathways of Periodontal Pathogens Entering the Brain: The Potential Role of Treponema denticola in Tracing Alzheimer’s Disease Pathology

Alzheimer’s Disease (AD) is a complex neurodegenerative disease and remains the most common form of dementia. The pathological features include amyloid (Aβ) accumulation, neurofibrillary tangles (NFTs), neural and synaptic loss, microglial cell activation, and an increased blood–brain barrier permea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pisani, Flavio, Pisani, Valerio, Arcangeli, Francesca, Harding, Alice, Singhrao, Simarjit Kaur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368682/ https://www.ncbi.nlm.nih.gov/pubmed/35954742 http://dx.doi.org/10.3390/ijerph19159386

Ejemplares similares

Treponema denticola Has the Potential to Cause Neurodegeneration in the Midbrain via the Periodontal Route of Infection—Narrative Review
por: Pisani, Flavio, et al.
Publicado: (2023)

Locus Coeruleus Dysfunction and Trigeminal Mesencephalic Nucleus Degeneration: A Cue for Periodontal Infection Mediated Damage in Alzheimer’s Disease?
por: Pisani, Flavio, et al.
Publicado: (2023)

Treponema denticola as a prognostic biomarker for periodontitis in dogs
por: Kwon, Daehyun, et al.
Publicado: (2022)

Intracellular localization of Treponema denticola chymotrypsin-like proteinase in chronic periodontitis
por: Marttila, Emilia, et al.
Publicado: (2014)

Treponema denticola interactions with host proteins
por: Fenno, J. Christopher
Publicado: (2012)

Binding properties of Treponema denticola lipooligosaccharide
por: Grenier, Daniel
Publicado: (2013)

Antibody and T Cell Responses to Fusobacterium nucleatum and Treponema denticola in Health and Chronic Periodontitis
por: Shin, Jieun, et al.
Publicado: (2013)

Diversity of Treponema denticola and Other Oral Treponeme Lineages in Subjects with Periodontitis and Gingivitis
por: Zeng, Huihui, et al.
Publicado: (2021)

Treponema denticola enolase contributes to the production of antibodies against ENO1 but not to the progression of periodontitis
por: Lee, Ahreum, et al.
Publicado: (2018)

1317. Porphyromonas gingivalis and Treponema denticola Induce Alzheimer's Disease Biomarkers in Mice
por: Butler, Catherine A, et al.
Publicado: (2023)

Transcriptional Profiles of Treponema denticola in Response to Environmental Conditions
por: McHardy, Ian, et al.
Publicado: (2010)

Porphyromonas gingivalis and Treponema denticola Exhibit Metabolic Symbioses
por: Tan, Kheng H., et al.
Publicado: (2014)

Metabolic cooperativity between Porphyromonas gingivalis and Treponema denticola
por: Kin, Lin Xin, et al.
Publicado: (2020)

Detection of Treponema Denticola in Symptomatic Apical Periodontitis and in Symptomatic Apical Abscesses by Real-Time PCR
por: Ozbek, Selcuk M., et al.
Publicado: (2009)

Porphyromonas gingivalis and Treponema denticola Mixed Microbial Infection in a Rat Model of Periodontal Disease
por: Verma, Raj K., et al.
Publicado: (2010)

Multilocus sequence analysis of Treponema denticola strains of diverse origin
por: Mo, Sisu, et al.
Publicado: (2013)

Porphyromonas gingivalis and Treponema denticola Synergistic Polymicrobial Biofilm Development
por: Zhu, Ying, et al.
Publicado: (2013)

Transcriptional Responses of Treponema denticola to Other Oral Bacterial Species
por: Sarkar, Juni, et al.
Publicado: (2014)

Pathogenicity of Treponema denticola Wild-Type and Mutant Strain Tested by an Active Mode of Periodontal Infection Using Microinjection
por: Izard, Jacques, et al.
Publicado: (2012)

Treponema denticola-Induced RASA4 Upregulation Mediates Cytoskeletal Dysfunction and MMP-2 Activity in Periodontal Fibroblasts
por: Malone, Erin Trent, et al.
Publicado: (2021)

Genomic and Metagenomic Analysis of Diversity-Generating Retroelements Associated with Treponema denticola
por: Nimkulrat, Sutichot, et al.
Publicado: (2016)

The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis
por: Ng, Hong Min, et al.
Publicado: (2019)

Approaches to Understanding Mechanisms of Dentilisin Protease Complex Expression in Treponema denticola
por: Goetting-Minesky, M. Paula, et al.
Publicado: (2021)

Detection of Porphyromonas gingivalis and Treponema denticola in chronic and aggressive periodontitis patients: A comparative polymerase chain reaction study
por: Kumawat, Ramniwas M., et al.
Publicado: (2016)

Treponema denticola TroR is a manganese- and iron-dependent transcriptional repressor
por: Brett, Paul J, et al.
Publicado: (2008)

Major Membrane Protein TDE2508 Regulates Adhesive Potency in Treponema denticola
por: Abiko, Yuki, et al.
Publicado: (2014)

Metagenomic Analysis Reveals Presence of Treponema denticola in a Tissue Biopsy of the Iceman
por: Maixner, Frank, et al.
Publicado: (2014)

Treponema denticola Induces Neuronal Apoptosis by Promoting Amyloid-β Accumulation in Mice
por: Wu, Linrui, et al.
Publicado: (2022)

The central region of the msp gene of Treponema denticola has sequence heterogeneity among clinical samples, obtained from patients with periodontitis
por: Gaibani, Paolo, et al.
Publicado: (2010)

Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Treponema denticola / Prevotella intermedia Co-Infection Are Associated with Severe Periodontitis in a Thai Population
por: Torrungruang, Kitti, et al.
Publicado: (2015)

Genome-Wide Relatedness of Treponema pedis, from Gingiva and Necrotic Skin Lesions of Pigs, with the Human Oral Pathogen Treponema denticola
por: Svartström, Olov, et al.
Publicado: (2013)

Evaluation of ciprofloxacin and metronidazole encapsulated biomimetic nanomatrix gel on Enterococcus faecalis and Treponema denticola
por: Kaushik, Sagar N, et al.
Publicado: (2015)

Characterization of Treponema denticola Mutants Defective in the Major Antigenic Proteins, Msp and TmpC
por: Abiko, Yuki, et al.
Publicado: (2014)

Characterization of a potential ABC-type bacteriocin exporter protein from Treponema denticola
por: Tanaka-Kumazawa, Kimiko, et al.
Publicado: (2016)

Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
por: Nieminen, Mikko T, et al.
Publicado: (2018)

Molecular docking analysis of thiazo inhibitors with the virulent factor cystalysin from Treponema denticola
por: Andrew, Serafina, et al.
Publicado: (2023)

Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum
por: Grenier, Daniel
Publicado: (2013)

Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma
por: Kylmä, Anna Kaisa, et al.
Publicado: (2018)

Investigation of the potential regulator proteins associated with the expression of major surface protein and dentilisin in Treponema denticola
por: Arai, Yuki, et al.
Publicado: (2020)

Molecular docking analysis of Indole based oxadiazoles with the H-binding protein from Treponema denticola
por: Kumaran, Poojitha, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f9n6j6bpchba2vph8v9dm6pv41