Associations of Dynapenic Obesity and Sarcopenic Obesity with the Risk of Complications in COVID-19

Ageing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle mass or reduced grip strength, it results in s...

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Detalles Bibliográficos
Autores principales: Pérez-Campos Mayoral, Laura, Matias-Cervantes, Carlos Alberto, Pérez-Campos, Eduardo, Romero Díaz, Carlos, Laguna Barrios, Luis Ángel, Pina Canseco, María del Socorro, Martínez Cruz, Margarito, Pérez-Campos Mayoral, Eduardo, Solórzano Mata, Carlos Josué, Rodal Canales, Francisco Javier, Martínez Ruíz, Héctor, Hernández-Huerta, María Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368708/
https://www.ncbi.nlm.nih.gov/pubmed/35955411
http://dx.doi.org/10.3390/ijms23158277
Descripción
Sumario:Ageing is associated with changes in body composition, such as low muscle mass (sarcopenia), decreased grip strength or physical function (dynapenia), and accumulation of fat mass. When the accumulation of fat mass synergistically accompanies low muscle mass or reduced grip strength, it results in sarcopenic obesity and dynapenic obesity, respectively. These types of obesity contribute to the increased risk of cardiovascular disease and mortality in the elderly, which could increase the damage caused by COVID-19. In this review, we associated factors that could generate a higher risk of COVID-19 complications in dynapenic obesity and sarcopenic obesity. For example, skeletal muscle regulates the expression of inflammatory cytokines and supports metabolic stress in pulmonary disease; hence, the presence of dynapenic obesity or sarcopenic obesity could be related to a poor prognosis in COVID-19 patients.

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