Pre-Synaptic GABA(A) in NaV1.8(+) Primary Afferents Is Required for the Development of Punctate but Not Dynamic Mechanical Allodynia following CFA Inflammation

Hypersensitivity to mechanical stimuli is a cardinal symptom of neuropathic and inflammatory pain. A reduction in spinal inhibition is generally considered a causal factor in the development of mechanical hypersensitivity after injury. However, the extent to which presynaptic inhibition contributes...

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Detalles Bibliográficos
Autores principales: Liu, Sheng, Bonalume, Veronica, Gao, Qi, Chen, Jeremy Tsung-Chieh, Rohr, Karl, Hu, Jing, Carr, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368720/
https://www.ncbi.nlm.nih.gov/pubmed/35954234
http://dx.doi.org/10.3390/cells11152390

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