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Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment
Stroke is the leading cause of death and neurological disorders worldwide. However, diagnostic techniques and treatments for stroke patients are still limited for certain types of stroke. Intensive research has been conducted so far to find suitable diagnostic techniques and treatments, but so far t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368737/ https://www.ncbi.nlm.nih.gov/pubmed/35955498 http://dx.doi.org/10.3390/ijms23158367 |
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author | Lee, Eun Chae Ha, Tae Won Lee, Dong-Hun Hong, Dong-Yong Park, Sang-Won Lee, Ji Young Lee, Man Ryul Oh, Jae Sang |
author_facet | Lee, Eun Chae Ha, Tae Won Lee, Dong-Hun Hong, Dong-Yong Park, Sang-Won Lee, Ji Young Lee, Man Ryul Oh, Jae Sang |
author_sort | Lee, Eun Chae |
collection | PubMed |
description | Stroke is the leading cause of death and neurological disorders worldwide. However, diagnostic techniques and treatments for stroke patients are still limited for certain types of stroke. Intensive research has been conducted so far to find suitable diagnostic techniques and treatments, but so far there has been no success. In recent years, various studies have drawn much attention to the clinical value of utilizing the mechanism of exosomes, low toxicity, biodegradability, and the ability to cross the blood–brain barrier. Recent studies have been reported on the use of biomarkers and protective and recovery effects of exosomes derived from stem cells or various cells in the diagnostic stage after stroke. This review focuses on publications describing changes in diagnostic biomarkers of exosomes following various strokes and processes for various potential applications as therapeutics. |
format | Online Article Text |
id | pubmed-9368737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93687372022-08-12 Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment Lee, Eun Chae Ha, Tae Won Lee, Dong-Hun Hong, Dong-Yong Park, Sang-Won Lee, Ji Young Lee, Man Ryul Oh, Jae Sang Int J Mol Sci Review Stroke is the leading cause of death and neurological disorders worldwide. However, diagnostic techniques and treatments for stroke patients are still limited for certain types of stroke. Intensive research has been conducted so far to find suitable diagnostic techniques and treatments, but so far there has been no success. In recent years, various studies have drawn much attention to the clinical value of utilizing the mechanism of exosomes, low toxicity, biodegradability, and the ability to cross the blood–brain barrier. Recent studies have been reported on the use of biomarkers and protective and recovery effects of exosomes derived from stem cells or various cells in the diagnostic stage after stroke. This review focuses on publications describing changes in diagnostic biomarkers of exosomes following various strokes and processes for various potential applications as therapeutics. MDPI 2022-07-28 /pmc/articles/PMC9368737/ /pubmed/35955498 http://dx.doi.org/10.3390/ijms23158367 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lee, Eun Chae Ha, Tae Won Lee, Dong-Hun Hong, Dong-Yong Park, Sang-Won Lee, Ji Young Lee, Man Ryul Oh, Jae Sang Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment |
title | Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment |
title_full | Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment |
title_fullStr | Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment |
title_full_unstemmed | Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment |
title_short | Utility of Exosomes in Ischemic and Hemorrhagic Stroke Diagnosis and Treatment |
title_sort | utility of exosomes in ischemic and hemorrhagic stroke diagnosis and treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368737/ https://www.ncbi.nlm.nih.gov/pubmed/35955498 http://dx.doi.org/10.3390/ijms23158367 |
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