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Targeting Tumor Acidosis and Regulatory T Cells Unmasks Anti-Metastatic Potential of Local Tumor Ablation in Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is an immunologically heterogenous disease that lacks clinically actionable targets and is more likely to progress to metastatic disease than other types of breast cancer. Tumor ablation has been used to increase response rates to checkpoint inhibitors, which rem...

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Detalles Bibliográficos
Autores principales: Nief, Corrine A., Gonzales, Alana, Chelales, Erika, Agudogo, Júlia Sroda, Crouch, Brian T., Nair, Smita K., Ramanujam, Nirmala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368760/
https://www.ncbi.nlm.nih.gov/pubmed/35955613
http://dx.doi.org/10.3390/ijms23158479