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An Adaptive Role for DNA Double-Strand Breaks in Hippocampus-Dependent Learning and Memory

DNA double-strand breaks (DSBs), classified as the most harmful type of DNA damage based on the complexity of repair, lead to apoptosis or tumorigenesis. In aging, DNA damage increases and DNA repair decreases. This is exacerbated in disease, as post-mortem tissue from patients diagnosed with mild c...

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Detalles Bibliográficos
Autores principales: Weber Boutros, Sydney, Unni, Vivek K., Raber, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368779/
https://www.ncbi.nlm.nih.gov/pubmed/35955487
http://dx.doi.org/10.3390/ijms23158352

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