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An Adaptive Role for DNA Double-Strand Breaks in Hippocampus-Dependent Learning and Memory
DNA double-strand breaks (DSBs), classified as the most harmful type of DNA damage based on the complexity of repair, lead to apoptosis or tumorigenesis. In aging, DNA damage increases and DNA repair decreases. This is exacerbated in disease, as post-mortem tissue from patients diagnosed with mild c...
Autores principales: | Weber Boutros, Sydney, Unni, Vivek K., Raber, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368779/ https://www.ncbi.nlm.nih.gov/pubmed/35955487 http://dx.doi.org/10.3390/ijms23158352 |
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