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Different In Vitro-Generated MUTZ-3-Derived Dendritic Cell Types Secrete Dexosomes with Distinct Phenotypes and Antigen Presentation Potencies

Human dendritic cell (DC) dexosomes were evaluated for their function and preclinical validation for vaccines. Dexosomes are small DC-secreted vesicles that contain absorbing immune signals. Vaccine manufacturing requires a significant number of monocyte-derived DCs (Mo-DCs) from donor blood; thus,...

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Detalles Bibliográficos
Autores principales: Sakamoto, Takuya, Koya, Terutsugu, Togi, Misa, Yoshida, Kenichi, Kato, Tomohisa, Ishigaki, Yasuhito, Shimodaira, Shigetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368791/
https://www.ncbi.nlm.nih.gov/pubmed/35955496
http://dx.doi.org/10.3390/ijms23158362