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Different In Vitro-Generated MUTZ-3-Derived Dendritic Cell Types Secrete Dexosomes with Distinct Phenotypes and Antigen Presentation Potencies
Human dendritic cell (DC) dexosomes were evaluated for their function and preclinical validation for vaccines. Dexosomes are small DC-secreted vesicles that contain absorbing immune signals. Vaccine manufacturing requires a significant number of monocyte-derived DCs (Mo-DCs) from donor blood; thus,...
Autores principales: | Sakamoto, Takuya, Koya, Terutsugu, Togi, Misa, Yoshida, Kenichi, Kato, Tomohisa, Ishigaki, Yasuhito, Shimodaira, Shigetaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368791/ https://www.ncbi.nlm.nih.gov/pubmed/35955496 http://dx.doi.org/10.3390/ijms23158362 |
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