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Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression
Lidocaine injection is a common treatment for tendon injuries. However, the evidence suggests that lidocaine is toxic to tendon cells. This study investigated the effects of lidocaine on cultured tendon cells, focusing on the molecular mechanisms underlying cell proliferation and extracellular matri...
Autores principales: | Chen, Yen-Chia, Chang, Hsiang-Ning, Pang, Jong-Hwei Su, Lin, Li-Ping, Chen, Jing-Min, Yu, Tung-Yang, Tsai, Wen-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368801/ https://www.ncbi.nlm.nih.gov/pubmed/35955918 http://dx.doi.org/10.3390/ijms23158787 |
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