Cargando…

FOXM1 Is a Novel Molecular Target of AFP-Positive Hepatocellular Carcinoma Abrogated by Proteasome Inhibition

Alpha-fetoprotein (AFP) is an oncofetal protein that is elevated in a subset of hepatocellular carcinoma (HCC) with poor prognosis, but the molecular target activated in AFP-positive HCC remains elusive. Here, we demonstrated that the transcription factor forkhead box M1 (FOXM1) is upregulated in AF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ru, Okada, Hikari, Yamashita, Taro, Nio, Kouki, Chen, Han, Li, Yingyi, Shimakami, Tetsuro, Takatori, Hajime, Arai, Kuniaki, Sakai, Yoshio, Yamashita, Tatsuya, Mizukoshi, Eishiro, Honda, Masao, Kaneko, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368809/ https://www.ncbi.nlm.nih.gov/pubmed/35955438 http://dx.doi.org/10.3390/ijms23158305

Ejemplares similares

Dickkopf-1 Promotes Angiogenesis and is a Biomarker for Hepatic Stem Cell-like Hepatocellular Carcinoma
por: Suda, Tsuyoshi, et al.
Publicado: (2022)

Plasma Antithrombin III Levels Can Be a Prognostic Factor in Liver Cirrhosis Patients with Portal Vein Thrombosis
por: Suda, Tsuyoshi, et al.
Publicado: (2023)

Inactivation of Transcriptional Repressor Capicua Confers Sorafenib Resistance in Human Hepatocellular Carcinoma
por: Hashiba, Tomomi, et al.
Publicado: (2020)

Investigation of Thrombosis Volume, Anticoagulants, and Recurrence Factors in Portal Vein Thrombosis with Cirrhosis
por: Suda, Tsuyoshi, et al.
Publicado: (2020)

Identification of a Transmembrane Protein Involved in Shear Stress Signaling and Hepatocarcinogenesis After a Sustained Virological Response to Hepatitis C Virus
por: Nishikawa, Masashi, et al.
Publicado: (2023)

BMP9‐ID1 signaling promotes EpCAM‐positive cancer stem cell properties in hepatocellular carcinoma
por: Chen, Han, et al.
Publicado: (2021)

Alterations in Hepatocellular Carcinoma-Specific Immune Responses Following Hepatitis C Virus Elimination by Direct-Acting Antivirals
por: Li, Shihui, et al.
Publicado: (2022)

Serum cytokine profiles predict survival benefits in patients with advanced hepatocellular carcinoma treated with sorafenib: a retrospective cohort study
por: Hayashi, Tomoyuki, et al.
Publicado: (2017)

Danaparoid sodium-based anticoagulation therapy for portal vein thrombosis in cirrhosis patients
por: Hayashi, Takehiro, et al.
Publicado: (2019)

BMP9-ID1 Signaling Activates HIF-1α and VEGFA Expression to Promote Tumor Angiogenesis in Hepatocellular Carcinoma
por: Chen, Han, et al.
Publicado: (2022)

MicroRNA‐10a Impairs Liver Metabolism in Hepatitis C Virus‐Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator‐Like 1
por: Horii, Rika, et al.
Publicado: (2019)

Peptide vaccine-treated, long-term surviving cancer patients harbor self-renewing tumor-specific CD8(+) T cells
por: Mizukoshi, Eishiro, et al.
Publicado: (2022)

Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation
por: Wang, Zijing, et al.
Publicado: (2019)

Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma
por: Honda, Masao, et al.
Publicado: (2013)

Upregulation of the Long Noncoding RNA HULC by Hepatitis C Virus and Its Regulation of Viral Replication
por: Kitabayashi, Juria, et al.
Publicado: (2020)

A novel α-fetoprotein-derived helper T-lymphocyte epitope with strong immunogenicity in patients with hepatocellular carcinoma
por: Tamai, Toshikatsu, et al.
Publicado: (2020)

Response to chemotherapy improves hepatic reserve for patients with hepatocellular carcinoma and Child–Pugh B cirrhosis
por: Terashima, Takeshi, et al.
Publicado: (2016)

Prognosis of type 1 autoimmune pancreatitis after corticosteroid therapy-induced remission in terms of relapse and diabetes mellitus
por: Miyazawa, Masaki, et al.
Publicado: (2017)

Decline in serum albumin concentration is a predictor of serious events in nonalcoholic fatty liver disease
por: Kawaguchi, Kazunori, et al.
Publicado: (2021)

Efficacy of a novel self-expandable metal stent with dumbbell-shaped flare ends for distal biliary obstruction due to unresectable pancreatic cancer
por: Miyazawa, Masaki, et al.
Publicado: (2022)

A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes
por: Sumiyadorj, Ariunaa, et al.
Publicado: (2022)

Super-Resolution Microscopy Analysis of Hepatitis B Viral cccDNA and Host Factors
por: Doan, Phuong Thi Bich, et al.
Publicado: (2023)

The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication
por: Shirasaki, Takayoshi, et al.
Publicado: (2018)

Potential efficacy of therapies targeting intrahepatic lesions after sorafenib treatment of patients with hepatocellular carcinoma
por: Terashima, Takeshi, et al.
Publicado: (2016)

Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells
por: Sakai, Yoshio, et al.
Publicado: (2019)

Safety and Long-Term Outcome of Intratumoral Injection of OK432-Stimulated Dendritic Cells for Hepatocellular Carcinomas After Radiofrequency Ablation
por: Kitahara, Masaaki, et al.
Publicado: (2020)

Preexisting Humoral Immunity Cross-Reacting with SARS-CoV-2 Might Prevent Death Due to COVID-19 in Critical Patients
por: Yamashita, Taro, et al.
Publicado: (2022)

Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice
por: Nishikawa, Tomoki, et al.
Publicado: (2020)

Management of biliary stricture in patients with IgG4-related sclerosing cholangitis
por: Miyazawa, Masaki, et al.
Publicado: (2020)

Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro
por: Murai, Kazuhisa, et al.
Publicado: (2018)

Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice
por: Shirasaki, Takayoshi, et al.
Publicado: (2021)

Eradication of angiomas by nylon loop snare ligation under total enteroscopy, in disseminated intravascular coagulation associated with blue rubber bleb nevus syndrome
por: Nakagawa, Hidetoshi, et al.
Publicado: (2022)

Beta-Hydroxyisovaleryl-Shikonin Eradicates Epithelial Cell Adhesion Molecule-Positive Liver Cancer Stem Cells by Suppressing dUTP Pyrophosphatase Expression
por: Asahina, Yoshiro, et al.
Publicado: (2023)

The evolving concept of liver cancer stem cells
por: Nio, Kouki, et al.
Publicado: (2017)

Hepatitis B virus X protein induces hepatic stem cell-like features in hepatocellular carcinoma by activating KDM5B
por: Wang, Xuyang, et al.
Publicado: (2017)

De Novo Emergence of Mesenchymal Stem-Like CD105(+) Cancer Cells by Cytotoxic Agents in Human Hepatocellular Carcinoma()()
por: Nomura, Yoshimoto, et al.
Publicado: (2017)

Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma
por: Hayashi, Takehiro, et al.
Publicado: (2017)

Immune responses of human T lymphocytes to novel hepatitis B virus-derived peptides
por: Yamamiya, Daisuke, et al.
Publicado: (2018)

Light alcohol consumption has the potential to suppress hepatocellular injury and liver fibrosis in non-alcoholic fatty liver disease
por: Yamada, Kazutoshi, et al.
Publicado: (2018)

Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet
por: Okada, Hikari, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0g4t9dsdm2273vmltbv3ggdnos