Cargando…

A Pilot Study on Peptidylarginine Deiminases and Protein Deimination in Animal Cancers across Vertebrate Species

PADs are a group of calcium-dependent enzymes that play key roles in inflammatory pathologies and have diverse roles in cancers. PADs cause irreversible post-translational modification of arginine to citrulline, leading to changes in protein function in different cellular compartments. PAD isozyme d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Inal, Jameel M., Hristova, Mariya, Lange, Sigrun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368843/ https://www.ncbi.nlm.nih.gov/pubmed/35955829 http://dx.doi.org/10.3390/ijms23158697

Ejemplares similares

Differential, Stage Dependent Detection of Peptidylarginine Deiminases and Protein Deimination in Lewy Body Diseases—Findings from a Pilot Study
por: Mercer, Audrey, et al.
Publicado: (2022)

Peptidylarginine Deiminases Post-Translationally Deiminate Prohibitin and Modulate Extracellular Vesicle Release and MicroRNAs in Glioblastoma Multiforme
por: Kosgodage, Uchini S., et al.
Publicado: (2018)

Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
por: Méchin, Marie-Claire, et al.
Publicado: (2020)

Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions
por: Kristmundsson, Árni, et al.
Publicado: (2021)

Peptidylarginine Deiminases—Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?
por: Lange, Sigrun, et al.
Publicado: (2017)

Putative Roles for Peptidylarginine Deiminases in COVID-19
por: Arisan, Elif Damla, et al.
Publicado: (2020)

Peptidylarginine Deiminase Inhibitors Reduce Bacterial Membrane Vesicle Release and Sensitize Bacteria to Antibiotic Treatment
por: Kosgodage, Uchini S., et al.
Publicado: (2019)

Peptidylarginine Deiminases as Drug Targets in Neonatal Hypoxic–Ischemic Encephalopathy
por: Lange, Sigrun
Publicado: (2016)

A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy
por: Kholia, Sharad, et al.
Publicado: (2015)

Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates
por: Lange, Sigrun, et al.
Publicado: (2014)

Peptidylarginine deiminases and extracellular vesicles: prospective drug targets and biomarkers in central nervous system diseases and repair
por: Lange, Sigrun
Publicado: (2020)

Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines
por: Uysal-Onganer, Pinar, et al.
Publicado: (2020)

Features of the citrullinating peptidylarginine deiminase enzymes
por: Vossenaar, ER, et al.
Publicado: (2004)

Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase
por: Damgaard, Dres, et al.
Publicado: (2017)

In vivo expression of peptidylarginine deiminase in Drosophila melanogaster
por: Mahneva, Olena, et al.
Publicado: (2020)

Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis
por: Demoruelle, M. Kristen, et al.
Publicado: (2021)

Role of peptidylarginine deiminase type 4 in gastric cancer
por: Xin, Jiang, et al.
Publicado: (2016)

Protein Deimination and Extracellular Vesicle Profiles in Antarctic Seabirds
por: Phillips, Richard A., et al.
Publicado: (2020)

Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis
por: Mohanan, Sunish, et al.
Publicado: (2012)

Analysis of the peptidylarginine deiminase V gene in rheumatoid arthritis
por: Caponi, L, et al.
Publicado: (2003)

Expression of Peptidylarginine Deiminase Type 4 in Ovarian Tumors
por: Wang, Lin, et al.
Publicado: (2010)

Protein Deimination Signatures in Plasma and Plasma-EVs and Protein Deimination in the Brain Vasculature in a Rat Model of Pre-Motor Parkinson’s Disease
por: Sancandi, Marco, et al.
Publicado: (2020)

The peptidylarginine deiminase gene is a conserved feature of Porphyromonas gingivalis
por: Gabarrini, Giorgio, et al.
Publicado: (2015)

Peptidylarginine deiminase 4 promotes age-related organ fibrosis
por: Martinod, Kimberly, et al.
Publicado: (2017)

Candida albicans-Induced NETosis Is Independent of Peptidylarginine Deiminase 4
por: Guiducci, Eva, et al.
Publicado: (2018)

Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis
por: Liu, Yudong, et al.
Publicado: (2018)

Microglial expression of peptidylarginine deiminase 2 in the prenatal rat brain
por: Asaga, Hiroaki, et al.
Publicado: (2007)

Peptidylarginine Deiminase 2 in Murine Antiviral and Autoimmune Antibody Responses
por: Mergaert, Aisha M., et al.
Publicado: (2022)

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice
por: Sodré, Fernanda M.C., et al.
Publicado: (2021)

Factors Associated with Promoted Proliferation of Osteosarcoma by Peptidylarginine Deiminase 4
por: Guo, Jianping, et al.
Publicado: (2021)

Peptidylarginine Deiminase 2 in Host Immunity: Current Insights and Perspectives
por: Wu, Zhenyu, et al.
Publicado: (2021)

Autocitrullination confers monocyte chemotactic properties to peptidylarginine deiminase 4
por: Yoshida, Ken, et al.
Publicado: (2023)

Post-Translational Protein Deimination Signatures in Serum and Serum-Extracellular Vesicles of Bos taurus Reveal Immune, Anti-Pathogenic, Anti-Viral, Metabolic and Cancer-Related Pathways for Deimination
por: Criscitiello, Michael F., et al.
Publicado: (2020)

Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)
por: Liu, Yi-Liang, et al.
Publicado: (2011)

Peptidylarginine deiminase isoforms expressed in the synovial membrane of rheumatoid arthritis patients
por: Chapuy-Regaud, S, et al.
Publicado: (2003)

Peptidylarginine deiminase type 2 is over expressed in the glaucomatous optic nerve
por: Cafaro, Thamara A., et al.
Publicado: (2010)

Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase
por: Damgaard, Dres, et al.
Publicado: (2016)

Generation and characterisation of Porphyromonas gingivalis mutant lacking peptidylarginine deiminase activity
por: Muñoz-Atienza, Estefanía, et al.
Publicado: (2017)

Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis
por: Young, Christine, et al.
Publicado: (2022)

Animal Models of Human Disease
por: Lange, Sigrun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rb2omfe9bqadk7mungbt9u1suh