Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents

Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine, MDP) is the smallest peptidoglycan fragment able to trigger an immune response by activating the NOD2 receptor. Structural modification of MDP can lead to analogues with improved immunostimulating properties. The aim of this work was to pre...

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Detalles Bibliográficos
Autores principales: Petrović Peroković, Vesna, Car, Željka, Bušljeta, Mia, Mihelec, Danijela, Paurević, Marija, Ivanković, Siniša, Stojković, Ranko, Ribić, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368957/
https://www.ncbi.nlm.nih.gov/pubmed/35955759
http://dx.doi.org/10.3390/ijms23158628

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