Monocarboxylate transporter upregulation in induced regulatory T cells promotes resistance to anti-PD-1 therapy in hepatocellular carcinoma patients

BACKGROUND: Programmed cell death-1 (PD-1) immune checkpoint inhibitors are not effective in treating all patients with hepatocellular carcinoma (HCC), and regulatory T cells (Tregs) may determine the resistance to anti-PD-1 therapy. METHODS: Patients were divided into two groups based on the clinic...

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Detalles Bibliográficos
Autores principales: Zhou, Jinren, Shao, Qing, Lu, Yunjie, Li, Yu, Xu, Zibo, Zhou, Bo, Chen, Qiuyang, Li, Xiangyu, Xu, Xiaozhang, Pan, Yufeng, Deng, Zhenhua, Wang, Yiming, Yu, Yue, Gu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9368998/
https://www.ncbi.nlm.nih.gov/pubmed/35965549
http://dx.doi.org/10.3389/fonc.2022.960066

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