Cargando…

The Acute Effects of Leptin on the Contractility of Isolated Rat Atrial and Ventricular Cardiomyocytes

Leptin is a pleiotropic peptide playing an important role in the regulation of cardiac functions. It is not clear whether leptin directly modulates the mechanical function of atrial cardiomyocytes. We compared the acute effects of leptin on the characteristics of mechanically non-loaded sarcomere sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khokhlova, Anastasia, Myachina, Tatiana, Butova, Xenia, Kochurova, Anastasia, Polyakova, Ekaterina, Galagudza, Michael, Solovyova, Olga, Kopylova, Galina, Shchepkin, Daniil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369024/ https://www.ncbi.nlm.nih.gov/pubmed/35955485 http://dx.doi.org/10.3390/ijms23158356

Ejemplares similares

The inter-chamber differences in the contractile function between left and right atrial cardiomyocytes in atrial fibrillation in rats
por: Butova, Xenia, et al.
Publicado: (2023)

Peculiarities of the Acetylcholine Action on the Contractile Function of Cardiomyocytes from the Left and Right Atria in Rats
por: Butova, Xenia, et al.
Publicado: (2022)

Type 1 Diabetes Impairs Cardiomyocyte Contractility in the Left and Right Ventricular Free Walls but Preserves It in the Interventricular Septum
por: Khokhlova, Anastasia, et al.
Publicado: (2022)

Contractile State Dependent Sarcomere Length Variability in Isolated Guinea-Pig Cardiomyocytes
por: Lookin, Oleg, et al.
Publicado: (2022)

Generative adversarial networks for construction of virtual populations of mechanistic models: simulations to study Omecamtiv Mecarbil action
por: Parikh, Jaimit, et al.
Publicado: (2021)

A combined Langendorff-injection technique for simultaneous isolation of single cardiomyocytes from atria and ventricles of the rat heart
por: Butova, X.A., et al.
Publicado: (2020)

The Effects of Mechanical Preload on Transmural Differences in Mechano-Calcium-Electric Feedback in Single Cardiomyocytes: Experiments and Mathematical Models
por: Khokhlova, Anastasia, et al.
Publicado: (2020)

Structural and Functional Properties of Kappa Tropomyosin
por: Kopylova, Galina V., et al.
Publicado: (2023)

Impact of Troponin in Cardiomyopathy Development Caused by Mutations in Tropomyosin
por: Nefedova, Victoria V., et al.
Publicado: (2022)

De Novo Asp219Val Mutation in Cardiac Tropomyosin Associated with Hypertrophic Cardiomyopathy
por: Tsaturyan, Andrey K., et al.
Publicado: (2022)

Novel Mutation Glu98Lys in Cardiac Tropomyosin Alters Its Structure and Impairs Myocardial Relaxation
por: Matyushenko, Alexander M., et al.
Publicado: (2023)

Interaction between Age and Obesity on Cardiomyocyte Contractile Function: Role of Leptin and Stress Signaling
por: Ren, Jun, et al.
Publicado: (2010)

Correction: Interaction between Age and Obesity on Cardiomyocyte Contractile Function: Role of Leptin and Stress Signaling
Publicado: (2014)

Retraction: Interaction between Age and Obesity on Cardiomyocyte Contractile Function: Role of Leptin and Stress Signaling
Publicado: (2022)

Fractalkine Depresses Cardiomyocyte Contractility
por: Taube, David, et al.
Publicado: (2013)

Assessment of contractility in intact ventricular cardiomyocytes using the dimensionless ‘Frank–Starling Gain’ index
por: Bollensdorff, Christian, et al.
Publicado: (2011)

In vitro effect of leptin on human cardiac contractility
por: Chaban, Ryan, et al.
Publicado: (2019)

Correction: Fractalkine Depresses Cardiomyocyte Contractility
por: Taube, David, et al.
Publicado: (2013)

Approaches to High-Throughput Analysis of Cardiomyocyte Contractility
por: Wright, Peter T., et al.
Publicado: (2020)

Extracellular Matrix in Regulation of Contractile System in Cardiomyocytes
por: Bildyug, Natalya
Publicado: (2019)

Length-Dependent Activation of Contractility and Ca-Transient Kinetics in Auxotonically Contracting Isolated Rat Ventricular Cardiomyocytes
por: Lookin, Oleg, et al.
Publicado: (2019)

Time- and Ventricular-Specific Expression Profiles of Genes Encoding Z-Disk Proteins in Pressure Overload Model of Left Ventricular Hypertrophy
por: Knyazeva, Anastasia, et al.
Publicado: (2019)

The importance of mechanical conditions in the testing of excitation abnormalities in a population of electro-mechanical models of human ventricular cardiomyocytes
por: Dokuchaev, Arsenii, et al.
Publicado: (2023)

Impact of A134 and E218 Amino Acid Residues of Tropomyosin on Its Flexibility and Function
por: Marchenko, Marina A., et al.
Publicado: (2020)

Hyperleptinemia results in systemic inflammation and the exacerbation of ischemia-reperfusion myocardial injury
por: Polyakova, Ekaterina A., et al.
Publicado: (2021)

Combination of personalized computational modeling and machine learning for optimization of left ventricular pacing site in cardiac resynchronization therapy
por: Dokuchaev, Arsenii, et al.
Publicado: (2023)

The GSTM2 C-Terminal Domain Depresses Contractility and Ca(2+) Transients in Neonatal Rat Ventricular Cardiomyocytes
por: Hewawasam, Ruwani P., et al.
Publicado: (2016)

Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae
por: Mannhardt, Ingra, et al.
Publicado: (2017)

Vinculin anchors contractile actin to the cardiomyocyte adherens junction
por: Merkel, Chelsea D., et al.
Publicado: (2019)

R4496C RyR2 mutation impairs atrial and ventricular contractility
por: Ferrantini, Cecilia, et al.
Publicado: (2016)

Left Atrial Contractility in Ischemic Heart Disease Patients with Left Ventricular Systolic Dysfunction
por: El Missiri, Ahmed, et al.
Publicado: (2016)

Effects of omecamtiv mecarbil on the contractile properties of skinned porcine left atrial and ventricular muscles
por: Nakanishi, Tomohiro, et al.
Publicado: (2022)

Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes
por: Kleinsorge, Mandy, et al.
Publicado: (2020)

Cholesterol Depletion Alters Cardiomyocyte Subcellular Signaling and Increases Contractility
por: Haque, Mohammed Z., et al.
Publicado: (2016)

Cholesterol depletion impairs contractile machinery in neonatal rat cardiomyocytes
por: Hissa, Barbara, et al.
Publicado: (2017)

Optical-flow based non-invasive analysis of cardiomyocyte contractility
por: Czirok, Andras, et al.
Publicado: (2017)

Hypochlorite-Modified LDL Induces Arrhythmia and Contractile Dysfunction in Cardiomyocytes
por: Koyani, Chintan N., et al.
Publicado: (2021)

Distinct Occurrence of Proarrhythmic Afterdepolarizations in Atrial Versus Ventricular Cardiomyocytes: Implications for Translational Research on Atrial Arrhythmia
por: Bögeholz, Nils, et al.
Publicado: (2018)

Neurohumoral, cardiac and inflammatory markers in the evaluation of heart failure severity and progression
por: Polyakova, Ekaterina A, et al.
Publicado: (2021)

Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension
por: Sareban, Mahdi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3dclpolfojchfgr559ivk08srh