Cargando…

Conjugation of the 9-kDa Isoform of Granulysin with Liposomes Potentiates Its Cytotoxicity

Nine kDa granulysin (GRNLY) is a human cytolytic protein secreted by cytotoxic T lymphocytes (CTL) and NK cells of the immune system whose demonstrated physiological function is the elimination of bacteria and parasites. In previous studies by our group, the anti-tumor capacity of recombinant granul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soler-Agesta, Ruth, Guerrero-Ochoa, Patricia, Marco-Brualla, Joaquín, Ibáñez-Pérez, Raquel, Marzo, Isabel, Martínez-Lostao, Luis, Anel, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369117/ https://www.ncbi.nlm.nih.gov/pubmed/35955839 http://dx.doi.org/10.3390/ijms23158705

Ejemplares similares

Antimicrobial Properties of an Immunomodulator - 15 kDa Human Granulysin
por: Wei, Hung-Mu, et al.
Publicado: (2016)

15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level
por: Castiello, Luciano, et al.
Publicado: (2011)

Preclinical Studies of Granulysin-Based Anti-MUC1-Tn Immunotoxins as a New Antitumoral Treatment
por: Guerrero-Ochoa, Patricia, et al.
Publicado: (2022)

Production of a Granulysin-Based, Tn-Targeted Cytolytic Immunotoxin Using Pulsed Electric Field Technology
por: Guerrero-Ochoa, Patricia, et al.
Publicado: (2020)

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation
por: Ouali, Boimpoundi Eunice Flavie, et al.
Publicado: (2020)

DR5 Up-Regulation Induced by Dichloroacetate Sensitizes Tumor Cells to Lipid Nanoparticles Decorated with TRAIL
por: Marco-Brualla, Joaquín, et al.
Publicado: (2023)

Granulysin expression and granulysin-mediated apoptosis in the peripheral blood of osteoarthritis patients
por: Drvar, Vedrana, et al.
Publicado: (2022)

SUN-LB62 Differential Regulation of 22 kDa and 20 kDa Growth Hormone Isoforms in Response to Acute Glucose Load and Moderate Intensity Exercise
por: Haenelt, Michael, et al.
Publicado: (2020)

PT-112 Induces Mitochondrial Stress and Immunogenic Cell Death, Targeting Tumor Cells with Mitochondrial Deficiencies
por: Soler-Agesta, Ruth, et al.
Publicado: (2022)

A Mutation in Mouse MT-ATP6 Gene Induces Respiration Defects and Opposed Effects on the Cell Tumorigenic Phenotype
por: Moreno-Loshuertos, Raquel, et al.
Publicado: (2023)

The cytoplasmic 60 kDa progesterone receptor isoform predominates in the human amniochorion and placenta at term
por: Taylor, Anthony H, et al.
Publicado: (2009)

GLI1 upregulates C-JUN through a specific 130-kDa isoform
por: AMABLE, LAUREN, et al.
Publicado: (2013)

ERK1b, a 46‐kDa ERK isoform that is differentially regulated by MEK
por: Yung, Yuval, et al.
Publicado: (2022)

Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2
por: Hamel-Côté, Geneviève, et al.
Publicado: (2019)

Data on physicochemical properties of LPEI 25 kDa, PEI“Max” 40 kDa and PEIpro™
por: Delafosse, Laurence, et al.
Publicado: (2016)

Are anti-glutamic acid decarboxylase 65-kDa isoform antibodies related to diabetes or brain tumor?
por: Maimaiti, Buajieerguli, et al.
Publicado: (2022)

Genetic deletion of the 67‐kDa isoform of glutamate decarboxylase alters conditioned fear behavior in rats
por: Fujihara, Kazuyuki, et al.
Publicado: (2020)

In Vitro Inhibition of Angiogenesis by Antibodies Directed against the 37kDa/67kDa Laminin Receptor
por: Khusal, Raksha, et al.
Publicado: (2013)

Elevated Granulysin Expression in Cytotoxic Lymphocytes from the Blood and Lesions of Patients with Lichen Planus
por: VIČIĆ, Marijana, et al.
Publicado: (2021)

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura
por: Xiao, Chengfeng, et al.
Publicado: (2004)

The 37kDa/67kDa Laminin Receptor acts as a receptor for Aβ(42) internalization
por: Da Costa Dias, Bianca, et al.
Publicado: (2014)

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity
por: Naidoo, Kerrilyn, et al.
Publicado: (2015)

Hypercapnic ventilatory response in mice lacking the 65 kDa isoform of Glutamic Acid Decarboxylase (GAD65)
por: Bissonnette, John M, et al.
Publicado: (2004)

Mutations in the ND2 Subunit of Mitochondrial Complex I Are Sufficient to Confer Increased Tumorigenic and Metastatic Potential to Cancer Cells
por: Marco-Brualla, Joaquín, et al.
Publicado: (2019)

Use of the Human Granulysin Transgenic Mice To Evaluate the Role of Granulysin Expression by CD8 T Cells in Immunity To Mycobacterium tuberculosis
por: Thakur, Preeti, et al.
Publicado: (2022)

Enhanced gene transfection efficiency by low-dose 25 kDa polyethylenimine by the assistance of 1.8 kDa polyethylenimine
por: Zhang, Hui, et al.
Publicado: (2018)

A cryptic promoter in the first exon of the SPG4 gene directs the synthesis of the 60-kDa spastin isoform
por: Mancuso, Giuseppe, et al.
Publicado: (2008)

An internal ribosome entry site element directs the synthesis of the 80 kDa isoforms of protein 4.1R
por: Lospitao, Eva, et al.
Publicado: (2008)

The 18 kDa Translocator Protein, Microglia and Neuroinflammation
por: Liu, Guo‐Jun, et al.
Publicado: (2014)

Monodisperse 130 kDa and 260 kDa Recombinant Human Hemoglobin Polymers as Scaffolds for Protein Engineering of Hemoglobin-Based Oxygen Carriers
por: Marquardt, David A., et al.
Publicado: (2012)

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene
por: Hu, Guang-Jing, et al.
Publicado: (2013)

Unveiling a Hidden Biomarker of Inflammation and Tumor Progression: The 65 kDa Isoform of MMP-9 New Horizons for Therapy
por: Rossano, Rocco, et al.
Publicado: (2021)

Selective quantification of the 22-kDa isoform of human growth hormone 1 in serum and plasma by immunocapture and LC–MS/MS
por: Sleumer, Bas, et al.
Publicado: (2022)

Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge Halichondria okadai
por: Matsumoto, Ryo, et al.
Publicado: (2012)

MALDI-TOF High Mass Calibration up to 200 kDa Using Human Recombinant 16 kDa Protein Histidine Phosphatase Aggregates
por: Ludwig, Katrin, et al.
Publicado: (2011)

Evaluation of the Prognostic Value of CD56 (140 kDa Isoform) Expression in Breast Cancer Tissues: an Eight-Year Retrospective Study
por: Niknam, Kianoush, et al.
Publicado: (2022)

Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei
por: Rehic, Edisa, et al.
Publicado: (2019)

The Role of Heat Shock Protein 70 kDa in Asthma
por: Shevchenko, Marina, et al.
Publicado: (2021)

Comparative Antimicrobial Activity of Granulysin against Bacterial Biothreat Agents
por: Endsley, Janice J, et al.
Publicado: (2009)

High Resolution Imaging Study of Interactions between the 37 kDa/67 kDa Laminin Receptor and APP, Beta-Secretase and Gamma-Secretase in Alzheimer's Disease
por: Jovanovic, Katarina, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_37368401lp77vcelmlpaf1fs7j