Isothiocyanates (ITCs) 1-(Isothiocyanatomethyl)-4-phenylbenzene and 1-Isothiocyanato-3,5-bis(trifluoromethyl)benzene—Aldehyde Dehydrogenase (ALDH) Inhibitors, Decreases Cisplatin Tolerance and Migratory Ability of NSCLC

One of the main treatment modalities for non-small-cell lung cancer (NSCLC) is cisplatin-based chemotherapy. However, the acquisition of cisplatin resistance remains a major problem. Existing chemotherapy regimens are often ineffective against cancer cells expressing aldehyde dehydrogenase (ALDH). A...

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Detalles Bibliográficos
Autores principales: Kryczka, Jolanta, Kryczka, Jakub, Janczewski, Łukasz, Gajda, Anna, Frączyk, Andrzej, Boncela, Joanna, Kolesińska, Beata, Brzeziańska-Lasota, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369118/
https://www.ncbi.nlm.nih.gov/pubmed/35955773
http://dx.doi.org/10.3390/ijms23158644

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