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c-Kit Induces Migration of Triple-Negative Breast Cancer Cells and Is a Promising Target for Tyrosine Kinase Inhibitor Treatment

Triple-negative breast cancer (TNBC) is associated with a poor prognosis and the absence of targeted therapy. c-Kit, a receptor tyrosine kinase (RTK), is considered a molecular target for anticancer drugs. Tyrosine kinase inhibitors (TKIs) recognizing c-Kit are used for the treatment of c-Kit-expres...

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Detalles Bibliográficos
Autores principales: López-Mejía, José A., Tallabs-Utrilla, Luis F., Salazar-Sojo, Pablo, Mantilla-Ollarves, Jessica C., Sánchez-Carballido, Manuel A., Rocha-Zavaleta, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369219/
https://www.ncbi.nlm.nih.gov/pubmed/35955836
http://dx.doi.org/10.3390/ijms23158702